If the atmosphere of the early Earth was hydrogen-rich, 1 it is reasonable to think that
hydrogenases, the enzymes enabling cells to use molecular hydrogen, were probably …

Carotenoids represent a large class of terpenoids characterized by an extensively
conjugated polyene chain. The conjugation system imparts carotenoids with excellent light …

In Escherichia coli, the main player in transcription regulation of fatty acid metabolism is the
FadR protein, which is involved in negative regulation of fatty acid degradation and in …

SUMMARY Iron-sulfur (Fe-S) clusters are required for critical biochemical pathways,
including respiration, photosynthesis, and nitrogen fixation. Assembly of these iron cofactors …

Broadly neutralizing antibodies (bNAbs) against HIV-1 Env V1V2 arise in multiple donors.
However, atomic-level interactions had previously been determined only with antibodies …

Membrane phospholipid synthesis is a vital facet of bacterial physiology. Although the
spectrum of phospholipid headgroup structures produced by bacteria is large, the key …

ABSTRACT The 37/67‐kDa laminin receptor (LAMR/RPSA) was originally identified as a 67‐
kDa binding protein for laminin, an extracellular matrix glycoprotein that provides cellular …

Ribonuclease H-like (RNHL) superfamily, also called the retroviral integrase superfamily,
groups together numerous enzymes involved in nucleic acid metabolism and implicated in …

Atomistic resolution is the standard for high-resolution biomolecular structures, but
experimental structural data are often at lower resolution. Coarse-grained models are also …

Biogenesis of iron-sulfur (Fesingle bondS) clusters in an essential process in living
organisms due to the critical role of Fesingle bondS cluster proteins in myriad cell functions …