Spatial structure, cooperation and competition in biofilms
Bacteria often live within matrix-embedded communities, termed biofilms, which are now
understood to be a major mode of microbial life. The study of biofilms has revealed their vast …
understood to be a major mode of microbial life. The study of biofilms has revealed their vast …
Bacterial quorum sensing and microbial community interactions
Many bacteria use a cell-cell communication system called quorum sensing to coordinate
population density-dependent changes in behavior. Quorum sensing involves production of …
population density-dependent changes in behavior. Quorum sensing involves production of …
LasR variant cystic fibrosis isolates reveal an adaptable quorum-sensing hierarchy in Pseudomonas aeruginosa
JB Feltner, DJ Wolter, CE Pope, MC Groleau… - MBio, 2016 - Am Soc Microbiol
Chronic Pseudomonas aeruginosa infections cause significant morbidity in patients with
cystic fibrosis (CF). Over years to decades, P. aeruginosa adapts genetically as it …
cystic fibrosis (CF). Over years to decades, P. aeruginosa adapts genetically as it …
The biogeography of infection revisited
Many microbial communities, including those involved in chronic human infections, are
patterned at the micron scale. In this Review, we summarize recent work that has defined the …
patterned at the micron scale. In this Review, we summarize recent work that has defined the …
Impact of quorum sensing signaling molecules in gram-negative bacteria on host cells: current understanding and future perspectives
Y ** Pseudomonas aeruginosa pathogenicity in the cystic fibrosis lung
Pseudomonas aeruginosa is a major pathogen in the lungs of cystic fibrosis (CF) patients.
However, it is now recognised that a diverse microbial community exists in the airways …
However, it is now recognised that a diverse microbial community exists in the airways …
Differential Regulation of the Phenazine Biosynthetic Operons by Quorum Sensing in Pseudomonas aeruginosa PAO1-N
The Pseudomonas aeruginosa quorum sensing (QS) network plays a key role in the
adaptation to environmental changes and the control of virulence factor production in this …
adaptation to environmental changes and the control of virulence factor production in this …
Quorum-sensing synthase mutations re-calibrate autoinducer concentrations in clinical isolates of Pseudomonas aeruginosa to enhance pathogenesis
KA Simanek, ML Schumacher, CP Mallery… - Nature …, 2023 - nature.com
Quorum sensing is a mechanism of bacterial communication that controls virulence gene
expression. Pseudomonas aeruginosa regulates virulence via two synthase/transcription …
expression. Pseudomonas aeruginosa regulates virulence via two synthase/transcription …
Social interactions in bacterial cell–cell signaling
Cooperation and conflict in microorganisms is being recognized as an important factor in the
organization and function of microbial communities. Many of the cooperative behaviors …
organization and function of microbial communities. Many of the cooperative behaviors …