How deep is the brain? The shallow brain hypothesis
Deep learning and predictive coding architectures commonly assume that inference in
neural networks is hierarchical. However, largely neglected in deep learning and predictive …
neural networks is hierarchical. However, largely neglected in deep learning and predictive …
Understanding the neural mechanisms of general anesthesia from interaction with sleep–wake state: a decade of discovery
WW Bao, S Jiang, WM Qu, WX Li, CH Miao… - Pharmacological …, 2023 - Elsevier
The development of cutting-edge techniques to study specific brain regions and neural
circuits that regulate sleep–wake brain states and general anesthesia (GA), has increased …
circuits that regulate sleep–wake brain states and general anesthesia (GA), has increased …
Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex
Cortical circuits are composed predominantly of pyramidal-to-pyramidal neuron
connections, yet their assembly during embryonic development is not well understood. We …
connections, yet their assembly during embryonic development is not well understood. We …
Predictive Processing: A Circuit Approach to Psychosis
Predictive processing is a computational framework that aims to explain how the brain
processes sensory information by making predictions about the environment and minimizing …
processes sensory information by making predictions about the environment and minimizing …
Sleep-like cortical dynamics during wakefulness and their network effects following brain injury
By connecting old and recent notions, different spatial scales, and research domains, we
introduce a novel framework on the consequences of brain injury focusing on a key role of …
introduce a novel framework on the consequences of brain injury focusing on a key role of …
Sleep and vigilance states: Embracing spatiotemporal dynamics
The classic view of sleep and vigilance states is a global stationary perspective driven by the
interaction between neuromodulators and thalamocortical systems. However, recent data …
interaction between neuromodulators and thalamocortical systems. However, recent data …
Thalamic contributions to the state and contents of consciousness
Consciousness can be conceptualized as varying along at least two dimensions: the global
state of consciousness and the content of conscious experience. Here, we highlight the …
state of consciousness and the content of conscious experience. Here, we highlight the …
Anesthesia and the neurobiology of consciousness
GA Mashour - Neuron, 2024 - cell.com
In the 19 th century, the discovery of general anesthesia revolutionized medical care. In the
21 st century, anesthetics have become indispensable tools to study consciousness. Here, I …
21 st century, anesthetics have become indispensable tools to study consciousness. Here, I …
Divergent neural activity in the VLPO during anesthesia and sleep
M Luo, X Fei, X Liu, Z **, Y Wang, M Xu - Advanced Science, 2023 - Wiley Online Library
The invention of general anesthesia (GA) represents a significant advance in modern
clinical practices. However, the exact mechanisms of GA are not entirely understood …
clinical practices. However, the exact mechanisms of GA are not entirely understood …
Ventrolateral periaqueductal gray GABAergic neurons promote arousal of sevoflurane anesthesia through cortico-midbrain circuit
Y Guo, Y Song, F Cao, A Li, X Hao, W Shi, Z Zhou… - Iscience, 2023 - cell.com
The mechanism of general anesthesia remains elusive. The ventrolateral periaqueductal
gray (vlPAG) in the midbrain regulates sleep and awake states. However, the role of vlPAG …
gray (vlPAG) in the midbrain regulates sleep and awake states. However, the role of vlPAG …