Is cancer biology different in older patients?

Y Van Herck, A Feyaerts, S Alibhai… - The Lancet Healthy …, 2021 - thelancet.com
Roughly 50% of cancer cases occur in people aged 65 years or older. Older people are
often diagnosed at a later stage and might receive less (intensive) treatment, which might …

Management of breast cancer in elderly individuals: recommendations of the International Society of Geriatric Oncology

H Wildiers, I Kunkler, L Biganzoli, J Fracheboud… - The lancet …, 2007 - thelancet.com
Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer
mortality in women worldwide. Elderly individuals make up a large part of the breast cancer …

Lumpectomy plus tamoxifen with or without irradiation in women age 70 years or older with early breast cancer: long-term follow-up of CALGB 9343

KS Hughes, LA Schnaper, JR Bellon… - Journal of clinical …, 2013 - ascopubs.org
Purpose To determine whether there is a benefit to adjuvant radiation therapy after breast-
conserving surgery and tamoxifen in women age≥ 70 years with early-stage breast cancer …

EORTC elderly task force position paper: approach to the older cancer patient

AG Pallis, C Fortpied, U Wedding, MC Van Nes… - European journal of …, 2010 - Elsevier
As a result of an increasing life expectancy, the incidence of cancer cases diagnosed in the
older population is rising. Indeed, cancer incidence is 11-fold higher in persons over the age …

Older female cancer patients: importance, causes, and consequences of undertreatment

C Bouchardy, E Rapiti, S Blagojevic… - Journal of Clinical …, 2007 - ascopubs.org
Despite increased interest in treatment of senior cancer patients, older patients are much too
often undertreated. This review aims to present data on treatment practices of older women …

Association between age at diagnosis and disease-specific mortality among postmenopausal women with hormone receptor–positive breast cancer

W van de Water, C Markopoulos, CJH van de Velde… - Jama, 2012 - jamanetwork.com
Context In addition to classic tumor-related prognostic factors, patient characteristics may be
associated with breast cancer outcome. Objective To assess the association between age at …

Invasive ductal carcinoma of the breast with the “triple-negative” phenotype: prognostic implications of EGFR immunoreactivity

G Viale, N Rotmensz, P Maisonneuve… - Breast cancer research …, 2009 - Springer
Invasive ductal carcinomas (IDC) of the breast with the triple negative phenotype (steroid
hormone receptor absent, negative HER2 status) are characterized by poor clinical …

Breast cancer in the elderly

D Crivellari, M Aapro, R Leonard… - Journal of clinical …, 2007 - ascopubs.org
Screening and adjuvant postoperative therapies have increased survival among women
with breast cancer. These tools are seldom applied in elderly patients, although the usually …

The impact of chemotherapy and survival prediction by machine learning in early Elderly Triple Negative Breast Cancer (eTNBC): a population based study from the …

K Huang, J Zhang, Y Yu, Y Lin, C Song - BMC geriatrics, 2022 - Springer
Purpose We aimed to analysis the impact of chemotherapy and establish prediction models
of prognosis in early elderly triple negative breast cancer (eTNBC) by using machine …

Breast cancer in the elderly—Should it be treated differently?

P Tesarova - Reports of Practical Oncology and …, 2013 - journals.viamedica.pl
Breast cancer risk increases with age and about a third of female breast cancers are
diagnosed in patients aged older than 70. Breast cancer in the elderly has, however, poorer …