Background Fatty acid esters of hydroxy fatty acids (FAHFAs) are a class of recently
discovered novel lipids gaining increasing attention due to their diverse biological roles …

Gas-phase ion/ion reactions can be used to alter analyte ion-types for subsequent
dissociation both quickly and efficiently without the need for altering analyte ionization …

Lipids and metabolites are of interest in many clinical and research settings because it is the
metabolome that is increasingly recognized as a more dynamic and sensitive molecular …

Several microglia-expressed genes have emerged as top risk variants for Alzheimer's
disease (AD). Impaired microglial phagocytosis is one of the main proposed outcomes by …

Fatty acid esters of hydroxy fatty acids (FAHFAs) are bioactive lipids that are positively
correlated with metabolic health in humans and mice. Since their discovery, understanding …

While various mass spectrometric approaches have been applied to lipid analysis,
unraveling the extensive structural diversity of lipids remains a significant challenge …

Cardiolipins (CLs) are comprised of two phosphatic acid moieties bound to a central glycerol
backbone and are substituted with four acyl chains. Consequently, a vast number of distinct …

Cerebrosides (n-HexCer) and glycosphingosines (n-HexSph) constitute two sphingolipid
subclasses. Both are comprised of a monosaccharide headgroup (glucose or galactose in …

With the continuous advancements in detection methods and the exploration of unknown
substances, an increasing number of bioactive compounds are being discovered. Fatty acid …

Heightened awareness regarding the implication of disturbances in lipid metabolism with
respect to prevalent human-related pathologies demands analytical techniques that provide …