Insights into metalloenzyme microenvironments: biomimetic metal complexes with a functional second coordination sphere
Non-covalent interactions in the second coordination sphere of metalloenzymes play a
significant role in determining activity and selectivity. The importance of these interactions is …
significant role in determining activity and selectivity. The importance of these interactions is …
Interactions of copper complexes with nucleic acids
A Erxleben - Coordination Chemistry Reviews, 2018 - Elsevier
Covalent or non-covalent interactions with DNA are the basis for many potential biomedical
applications of copper complexes, ranging from DNA structural probes and footprinting …
applications of copper complexes, ranging from DNA structural probes and footprinting …
Macrocyclic metal complexes for metalloenzyme mimicry and sensor development
T Joshi, B Graham, L Spiccia - Accounts of chemical research, 2015 - ACS Publications
Conspectus Examples of proteins that incorporate one or more metal ions within their
structure are found within a broad range of classes, including oxidases, oxidoreductases …
structure are found within a broad range of classes, including oxidases, oxidoreductases …
[HTML][HTML] Phosphodiester models for cleavage of nucleic acids
S Mikkola, T Lönnberg… - Beilstein journal of organic …, 2018 - beilstein-journals.org
Nucleic acids that store and transfer biological information are polymeric diesters of
phosphoric acid. Cleavage of the phosphodiester linkages by protein enzymes, nucleases …
phosphoric acid. Cleavage of the phosphodiester linkages by protein enzymes, nucleases …
Picolinate-Containing Macrocyclic Mn2+ Complexes as Potential MRI Contrast Agents
E Molnar, N Camus, V Patinec, GA Rolla… - Inorganic …, 2014 - ACS Publications
We report the synthesis of the ligand Hnompa (6-((1, 4, 7-triazacyclononan-1-yl) methyl)
picolinic acid) and a detailed characterization of the Mn2+ complexes formed by this ligand …
picolinic acid) and a detailed characterization of the Mn2+ complexes formed by this ligand …
Efficient hydrolytic cleavage of plasmid DNA by chloro-cobalt (II) complexes based on sterically hindered pyridyl tripod tetraamine ligands: Synthesis, crystal structure …
SS Massoud, RS Perkins, FR Louka, W Xu… - Dalton …, 2014 - pubs.rsc.org
Four new cobalt (II) complexes [Co (6-MeTPA) Cl] ClO4/PF6 (2/2a),[Co (6-Me2TPA) Cl]
ClO4/PF6 (3/3a),[Co (BPQA) Cl] ClO4/PF6 (4/4a) and [Co (BQPA) Cl] ClO4/PF6 (5/5a) as …
ClO4/PF6 (3/3a),[Co (BPQA) Cl] ClO4/PF6 (4/4a) and [Co (BQPA) Cl] ClO4/PF6 (5/5a) as …
Di and tetranuclear Cu (II) complexes with simple 2-aminoethylpyridine: Magnetic properties, phosphodiester hydrolysis, DNA binding/cleavage, cytotoxicity and …
Di and tetranuclear Cu (II) complexes,[Cu 2 (2-AEP) 4 (µ-Cl)](ClO 4) 3 (1) and [Cu 4 (µ 3-OH)
2 (µ 2-OH) 2 (2-AEP) 4 (µ 2-ClO 4) 2](ClO 4) 2 (2), with the simple 2-aminoethylpyridine (2 …
2 (µ 2-OH) 2 (2-AEP) 4 (µ 2-ClO 4) 2](ClO 4) 2 (2), with the simple 2-aminoethylpyridine (2 …
Cu (II)-TACN complexes selectively induce antitumor activity in HepG-2 cells via DNA damage and mitochondrial-ROS-mediated apoptosis
M Liu, XQ Song, YD Wu, J Qian, JY Xu - Dalton Transactions, 2020 - pubs.rsc.org
A new 1, 4, 7-triazacyclononane derivative, 4-benzyloxy-benzyl-1, 4, 7-triazacyclononane
(btacn), and three associated cyclen complexes, Cu (btacn) Cl2, Zn (btacn) Cl2 and [Cu …
(btacn), and three associated cyclen complexes, Cu (btacn) Cl2, Zn (btacn) Cl2 and [Cu …
Improving the stability and inertness of Cu (II) and Cu (I) complexes with methylthiazolyl ligands by tuning the macrocyclic structure
A tacn based ligand bearing two methylthiazolyl arms (no2th) was synthesized with the aim
to find ligands forming very stable and inert complexes with Cu (II) and Cu (I) in aqueous …
to find ligands forming very stable and inert complexes with Cu (II) and Cu (I) in aqueous …
Transesterification of RNA model induced by novel dinuclear copper (II) complexes with bis-tridentate imidazole derivatives
X Wang, J Shu, T Ni, C Xu, B Xu, X Liu, K Zhang… - JBIC Journal of …, 2023 - Springer
Two novel bis-tridentate imidazole derivatives were conveniently synthesized using a 'one-
pot'method. Their dinuclear (Cu2L1Cl4, Cu2L2Cl4) and mononuclear (CuL1Cl2, CuL2Cl2∙ …
pot'method. Their dinuclear (Cu2L1Cl4, Cu2L2Cl4) and mononuclear (CuL1Cl2, CuL2Cl2∙ …