Early evaluation of treatment response and prediction of disease evolution are key issues in
the management of people with multiple sclerosis (MS). In the past 20 years, MRI has …

Summary About 10–15% of patients with multiple sclerosis (MS) present with gradually
increasing neurological disability, a disorder known as primary-progressive multiple …

Electromagnetic source characterisation requires accurate volume conductor models
representing head geometry and the electrical conductivity field. Head tissue conductivity is …

Objective To determine gray matter (GM) atrophy rates in multiple sclerosis (MS) patients at
all stages of disease, and to identify predictors and clinical correlates of GM atrophy …

During the past 10 years, the intense involvement of the grey matter of the CNS in the
pathology of multiple sclerosis has become evident. On gross inspection, demyelination in …

Multiple sclerosis (MS) has been classically regarded as a white matter disease. However,
recent histopathological studies have convincingly shown that grey matter regions are also …

White matter tracts, which play a crucial role in the coordination of information flow between
different regions of grey matter, are particularly vulnerable to multiple sclerosis. Many …

Objective To determine the relation of gray matter (GM) and white matter (WM) brain
volumes, and WM lesion load, with clinical outcomes 20 years after first presentation with …

Multiple sclerosis (MS), the most frequent demyelinating disease, is characterized by a
variable disease course. The majority of patients starts with relapsing remitting (RR) …

Introduction Viscoelastic properties indicate structural alterations in biological tissues at
multiple scales with high sensitivity. Magnetic Resonance Elastography (MRE) is a novel …