Advances and challenges in precision imaging

H Hricak, ME Mayerhoefer, K Herrmann… - The Lancet …, 2025 - thelancet.com
Technological innovations in genomics and related fields have facilitated large sequencing
efforts, supported new biological discoveries in cancer, and spawned an era of liquid biopsy …

The role of total-body PET in drug development and evaluation: status and outlook

X Meng, X Kong, L **a, R Wu, H Zhu… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Total-body PET, an emerging technique, enables high-quality simultaneous total-body
dynamic PET acquisition and accurate kinetic analysis. It has the potential to facilitate the …

[1-11C]-Butanol Positron Emission Tomography reveals an impaired brain to nasal turbinates pathway in aging amyloid positive subjects

NH Mehta, X Wang, SA Keil, K **, L Zhou, K Lee… - Fluids and Barriers of …, 2024 - Springer
Background Reduced clearance of cerebrospinal fluid (CSF) has been suggested as a
pathological feature of Alzheimer's disease (AD). With extensive documentation in non …

[HTML][HTML] Long Axial Field of View PET/CT: Technical Aspects in Cardiovascular Diseases

TS Martinez-Lucio, OI Mendoza-Ibañez, W Liu… - Seminars in Nuclear …, 2024 - Elsevier
Positron emission tomography/computed tomography (PET/CT) plays a pivotal role in the
assessment of cardiovascular diseases (CVD), particularly in the context of ischemic heart …

High-Temporal-Resolution Kinetic Modeling of Lung Tumors with Dual-Blood Input Function Using Total-Body Dynamic PET

Y Wang, YG Abdelhafez, BA Spencer… - Journal of Nuclear …, 2024 - Soc Nuclear Med
The lungs are supplied by both the pulmonary arteries carrying deoxygenated blood
originating from the right ventricle and the bronchial arteries carrying oxygenated blood …

Quantitative PET imaging and modeling of molecular blood-brain barrier permeability

KJ Chung, YG Abdelhafez, BA Spencer, T Jones… - medRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Blood-brain barrier (BBB) disruption is involved in the pathogenesis and progression of
many neurological and systemic diseases. Non-invasive assessment of BBB permeability in …

Total-Body PET/CT Applications in Cardiovascular Diseases: A Perspective Document of the SNMMI Cardiovascular Council

RHJA Slart, FM Bengel, C Akincioglu… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Digital PET/CT systems with a long axial field of view have become available and are
emerging as the current state of the art. These new camera systems provide wider anatomic …

The impact of long axial field of view (LAFOV) PET on oncologic imaging

GJR Cook, IL Alberts, T Wagner, BM Fischer… - European Journal of …, 2024 - Elsevier
The development of long axial field of view (LAFOV) positron emission tomography coupled
with computed tomography (PET/CT) scanners might be considered the biggest step forward …

Performance and application of the total-body PET/CT scanner: a literature review

Y Sun, Z Cheng, J Qiu, W Lu - EJNMMI research, 2024 - Springer
Background The total-body positron emission tomography/computed tomography (PET/CT)
system, with a long axial field of view, represents the state-of-the-art PET imaging technique …

Current progress and future perspectives in total‐body positron emission tomography/computed tomography. Part II: Clinical applications

R Chen, T Sun, G Huang, Y Zhou, J Liu - iRADIOLOGY, 2024 - Wiley Online Library
Total‐body positron emission tomography (TB‐PET) has significantly advanced from initial
conception to global commercial availability. The high sensitivity of TB‐PET has led to …