A data science roadmap for open science organizations engaged in early-stage drug discovery
Abstract The Structural Genomics Consortium is an international open science research
organization with a focus on accelerating early-stage drug discovery, namely hit discovery …
organization with a focus on accelerating early-stage drug discovery, namely hit discovery …
Materials data science: current status and future outlook
SR Kalidindi, M De Graef - Annual Review of Materials Research, 2015 - annualreviews.org
The field of materials science and engineering is on the cusp of a digital data revolution.
After reviewing the nature of data science and Big Data, we discuss the features of materials …
After reviewing the nature of data science and Big Data, we discuss the features of materials …
Virtual screening web servers: designing chemical probes and drug candidates in the cyberspace
The interplay between life sciences and advancing technology drives a continuous cycle of
chemical data growth; these data are most often stored in open or partially open databases …
chemical data growth; these data are most often stored in open or partially open databases …
In silico repositioning of approved drugs for rare and neglected diseases
One approach to speed up drug discovery is to examine new uses for existing approved
drugs, so-called 'drug repositioning'or 'drug repurposing', which has become increasingly …
drugs, so-called 'drug repositioning'or 'drug repurposing', which has become increasingly …
Recent advancements in the development of anti-tuberculosis drugs
Modern chemotherapy has significantly improved patient outcomes against drug-sensitive
tuberculosis. However, the rapid emergence of drug-resistant tuberculosis, together with the …
tuberculosis. However, the rapid emergence of drug-resistant tuberculosis, together with the …
In silico drug repositioning–what we need to know
Drug repositioning, exemplified by sildenafil and thalidomide, is a promising way to explore
alternative indications for existing drugs. Recent research has shown that bioinformatics …
alternative indications for existing drugs. Recent research has shown that bioinformatics …
[LIVRE][B] Healthcare data analytics
CK Reddy, CC Aggarwal - 2015 - books.google.com
Supplying a comprehensive overview of healthcare analytics research, Healthcare Data
Analytics provides an understanding of the analytical techniques currently available to solve …
Analytics provides an understanding of the analytical techniques currently available to solve …
Data-driven medicinal chemistry in the era of big data
SJ Lusher, R McGuire, RC van Schaik… - Drug discovery today, 2014 - Elsevier
Science, and the way we undertake research, is changing. The increasing rate of data
generation across all scientific disciplines is providing incredible opportunities for data …
generation across all scientific disciplines is providing incredible opportunities for data …
Targeting Phenotypically Tolerant Mycobacterium tuberculosis
Two parallel revolutions were born in the golden era of antibiotics (~ 1940 to 1960). One
was a revolution in medicine as physicians went to war with microbes. The second was a …
was a revolution in medicine as physicians went to war with microbes. The second was a …