Diagnostic devices used in the point-of-care (POC) today play a critical role as tools to
provide essential medical surveillance data and to ensure that patients receive appropriate …

Ionic liquids (ILs) have been in utility since the beginning of the 1980s due to their vast
range of features, uses, and environmentally acceptable nature. They have been presented …

The preservation of labile biomolecules presents a major challenge in chemistry, and deep
eutectic solvents (DESs) have emerged as suitable environments for this purpose. However …

Monoclonal antibodies (mAbs) have revolutionised the biopharmaceutical market. Being
proteinaceous, mAbs are prone to chemical and physical instabilities. Various approaches …

Antibodies, such as immunoglobulin G (IgG), have a pivotal role as biopharmaceuticals
capable of treating a wide variety of diseases. However, IgG is a protein, hence, it can easily …

Novel drug candidates are continuously being developed to combat the most life-
threatening diseases; however, many promising protein therapeutics are dropped from the …

Among antibody-based biopharmaceuticals, immunoglobulin G (IgG) plays a central role.
However, IgG is a protein and as such easily loses stability, thus compromising its use as an …

Distribution functions are used to investigate the interactions between the components of
condensed-phase systems, while allowing the computation of thermodynamic properties …

The aggregation of therapeutic proteins is potentially encountered during various steps such
as bioprocessing, formulation, storage, transportation and administration. The aggregation …

Adequate stability, manufacturability, and safety are crucial to bringing an antibody-based
biotherapeutic to the market. Following the concept of holistic in silico developability, we …