The potential for commonly used anesthetics and sedatives to cause neuroapoptosis and
other neurodegenerative changes in the develo** mammalian brain has become evident …

Background Whether exposure to a single general anaesthetic (GA) in early childhood
causes long-term neurodevelopmental problems remains unclear. Methods …

Background Few studies of how exposure of children to anesthesia may affect
neurodevelopment employ comprehensive neuropsychological assessments. This study …

Background In laboratory animals, exposure to most general anaesthetics leads to
neurotoxicity manifested by neuronal cell death and abnormal behaviour and cognition …

Importance Exposure of young animals to commonly used anesthetics causes neurotoxicity
including impaired neurocognitive function and abnormal behavior. The potential …

Background Exposure of young animals to general anesthesia (GA) causes
neurodegeneration and lasting behavioral abnormalities; whether these findings translate to …

BACKGROUND: Anesthetics induce widespread cell death, permanent neuronal deletion,
and neurocognitive impairment in immature animals, raising substantial concerns about …

Background Retrospective studies in humans have shown a higher prevalence of learning
disabilities in children that received multiple exposures to general anesthesia before the age …

Background: Animal studies demonstrate general anesthetic (GA) toxicity in the develo**
brain. Clinical reports raise concern, but the risk of GA exposure to neurodevelopment in …

A recent US Food and Drug Administration warning advised that prolonged or repeated
exposure to general anesthetics may affect neurodevelopment in children. This warning is …