Protease inhibitors from plants as therapeutic agents-a review

MS Cid-Gallegos, LJ Corzo-Ríos… - Plant Foods for Human …, 2022 - Springer
Plant-based diets are a great source of protease inhibitors (PIs). Two of the most well-known
families of PIs are Bowman-Birk inhibitors (BBI) and Kunitz-type inhibitors (KTI). The first …

Biotechnological, biomedical, and agronomical applications of plant protease inhibitors with high stability: A systematic review

J Cotabarren, D Lufrano, MG Parisi, WD Obregón - Plant Science, 2020 - Elsevier
Protease inhibitors (PIs) are regulatory proteins found in numerous animal tissues and
fluids, plants, and microorganisms that reduce and inhibit the exacerbated and uncontrolled …

Plant protease inhibitors as emerging antimicrobial peptide agents: a Comprehensive Review

MG Parisi, B Ozón, SM Vera González, J García-Pardo… - Pharmaceutics, 2024 - mdpi.com
Antimicrobial peptides (AMPs) are important mediator molecules of the innate defense
mechanisms in a wide range of living organisms, including bacteria, mammals, and plants …

DbGTi: Thermostable trypsin inhibitor from Dioscorea bulbifera L. ground tubers: assessment of antioxidant and antibacterial properties and cytotoxicity evaluation …

S Jegadheeshwari, M Velayutham… - International Journal of …, 2024 - Elsevier
Oxidative stress disorders and diseases caused by drug-resistant bacteria have emerged as
significant public health concerns. Plant-based medications like protease inhibitors are …

The forgotten 2S albumin proteins: Importance, structure, and biotechnological application in agriculture and human health

PFN Souza - International Journal of Biological Macromolecules, 2020 - Elsevier
Abstract 2S albumin proteins are a group of important seed storage proteins (SSPs)
essential to seeds at early and late developmental stages, by providing amino acids and …

Tag-specific affinity purification of recombinant proteins by using molecularly imprinted polymers

LN Gómez-Arribas, JL Urraca, E Benito-Peña… - Analytical …, 2019 - ACS Publications
Epitope tagging is widely used to fuse a known epitope to proteins for which no affinity
receptor is available by using recombinant DNA technology. One example is FLAG epitope …

From naturally-sourced protease inhibitors to new treatments for fungal infections

D Gutierrez-Gongora, J Geddes-McAlister - Journal of Fungi, 2021 - mdpi.com
Proteases are involved in a broad range of physiological processes, including host invasion
by fungal pathogens, and enzymatic inhibition is a key molecular mechanism controlling …

Recombinant expression of insoluble enzymes in Escherichia coli: a systematic review of experimental design and its manufacturing implications

S Mital, G Christie, D Dikicioglu - Microbial cell factories, 2021 - Springer
Recombinant enzyme expression in Escherichia coli is one of the most popular methods to
produce bulk concentrations of protein product. However, this method is often limited by the …

A Reconstructed Common Ancestor of the Fatty Acid Photo‐decarboxylase Clade Shows Photo‐decarboxylation Activity and Increased Thermostability

Y Sun, E Calderini, R Kourist - ChemBioChem, 2021 - Wiley Online Library
Light‐dependent enzymes are a rare type of biocatalyst with high potential for research and
biotechnology. A recently discovered fatty acid photo‐decarboxylase from Chlorella …

[HTML][HTML] Impact of the structural modifications of potato protein in the digestibility process under semi-dynamic simulated human gastrointestinal in vitro system

L Jiménez-Munoz, ED Tsochatzis, M Corredig - Nutrients, 2022 - mdpi.com
The raising consumer demand for plant-derived proteins has led to an increased production
of alternative protein ingredients with varying processing histories. In this study, we used a …