1. From avascular to vascular It is clear that for vasculogenesis and angiogenesis to
effectively proceed during physiological and pathological From the earliest stages, the …

The endoderm germ layer contributes to the respiratory and gastrointestinal tracts and to all
of their associated organs. Over the past decade, studies in vertebrate model organisms …

Here we delineate the ontogeny of the mammalian endoderm by generating 112,217 single-
cell transcriptomes, which represent all endoderm populations within the mouse embryo …

Thyroid gland organogenesis results in an organ the shape, size, and position of which are
largely conserved among adult individuals of the same species, thus suggesting that genetic …

During early mouse embryogenesis, temporal and spatial regulation of gene expression and
cell signalling influences lineage specification, embryonic polarity, the patterning of tissue …

The third and fourth weeks of gestation in primates are marked by several developmental
milestones, including gastrulation and the formation of organ primordia. However, our …

The anterior-posterior axis of the mouse embryo is defined before formation of the primitive
streak, and axis specification and subsequent anterior development involves signaling from …

The evolution of embryo models | Nature Methods Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

The investigation into lineage allocation and early asymmetries in the pre-and peri-
implantation mouse embryo is gaining momentum. As we review here, new insights have …

Studying the formation of the embryonic axes in mammals poses a special problem because
patterning of the embryo itself is a relatively late event in development. In the mouse, explicit …