The endoderm germ layer contributes to the respiratory and gastrointestinal tracts and to all
of their associated organs. Over the past decade, studies in vertebrate model organisms …

1. From avascular to vascular It is clear that for vasculogenesis and angiogenesis to
effectively proceed during physiological and pathological From the earliest stages, the …

Here we delineate the ontogeny of the mammalian endoderm by generating 112,217 single-
cell transcriptomes, which represent all endoderm populations within the mouse embryo …

The third and fourth weeks of gestation in primates are marked by several developmental
milestones, including gastrulation and the formation of organ primordia. However, our …

The evolution of embryo models | Nature Methods Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

The development of mouse embryos can be partially recapitulated by combining embryonic
stem cells (ESCs), trophoblast stem cells (TS), and extra-embryonic endoderm (XEN) stem …

The mouse embryo is the canonical model for mammalian preimplantation development.
Recent advances in single cell profiling allow detailed analysis of embryogenesis in other …

In this review, we present an overview of intestinal development and cellular differentiation
of the intestinal epithelium. The review is separated into two sections: Section one …

The primary function of the thyroid gland is to metabolize iodide by synthesizing thyroid
hormones, which are critical regulators of growth, development and metabolism in almost all …

The investigation into lineage allocation and early asymmetries in the pre-and peri-
implantation mouse embryo is gaining momentum. As we review here, new insights have …