Computational physiological models for individualised mechanical ventilation: a systematic literature review focussing on quality, availability, and clinical readiness
RSP Warnaar, MP Mulder, L Fresiello, AD Cornet… - Critical Care, 2023 - Springer
Background Individualised optimisation of mechanical ventilation (MV) remains
cumbersome in modern intensive care medicine. Computerised, model-based support …
cumbersome in modern intensive care medicine. Computerised, model-based support …
Predicting mechanically ventilated patients future respiratory system elastance–A stochastic modelling approach
Background and objective Respiratory mechanics of mechanically ventilated patients evolve
significantly with time, disease state and mechanical ventilation (MV) treatment. Existing …
significantly with time, disease state and mechanical ventilation (MV) treatment. Existing …
Low-cost structured light imaging of regional volume changes for use in assessing mechanical ventilation
Background Optimal setting of mechanical ventilators is critical for improving outcomes.
Accurate, predictive lung mechanics models are effective in optimizing MV settings, but only …
Accurate, predictive lung mechanics models are effective in optimizing MV settings, but only …
[HTML][HTML] Patient-ventilator asynchrony classification in mechanically ventilated patients: Model-based or machine learning method?
Background and objective Patient-ventilator asynchrony (PVA) is associated with poor
clinical outcomes and remains under-monitored. Automated PVA detection would enable …
clinical outcomes and remains under-monitored. Automated PVA detection would enable …
[HTML][HTML] A model-based quantification of nonlinear expiratory resistance in Plethysmographic data of COPD patients
T Lerios, JL Knopp, C Zilianti, M Pecchiari… - Computer Methods and …, 2025 - Elsevier
Background Chronic obstructive pulmonary disease (COPD) is characterised by airway
obstruction with an increase in airway resistance (R) to airflow in the lungs. An extreme case …
obstruction with an increase in airway resistance (R) to airflow in the lungs. An extreme case …
Model-based analysis of respiratory mechanics and parameters in critically ill mechanically ventilated patients
Mechanical ventilation (MV) parameters and other physiological parameters determined
from mechanically ventilated respiratory failure patients can be used to estimate patient …
from mechanically ventilated respiratory failure patients can be used to estimate patient …
Multi-level digital-twin models of pulmonary mechanics: correlation analysis of 3D CT lung volume and 2D Chest motion
Creating multi-level digital-twin models for mechanical ventilation requires a detailed
estimation of regional lung volume. An accurate generic map between 2D chest surface …
estimation of regional lung volume. An accurate generic map between 2D chest surface …
Estimating patient spontaneous breathing effort in mechanical ventilation using a b-splines function approach
Background: Patient work of breathing is a key clinical metric strongly to guide patient care
and weaning from mechanical ventilation (MV). Measurement requires added equipment …
and weaning from mechanical ventilation (MV). Measurement requires added equipment …
Ubiquity of models describing inspiratory effort dynamics in patients on pressure support ventilation
Mechanical Ventilation (MV) is an important therapy in the intensive care unit (ICU). Assisted
spontaneous breathing (ASB) MV modes are a key and growing part of MV care, as they …
spontaneous breathing (ASB) MV modes are a key and growing part of MV care, as they …
Identifying low-dimensional trajectories of mechanically-ventilated patient systems: Empirical phenotypes of joint patient+ care processes to enhance temporal …
Refined management of mechanically ventilation is an obvious target for improving patient
outcomes, but is impeded by the nature of data for study and hypothesis generation. The …
outcomes, but is impeded by the nature of data for study and hypothesis generation. The …