MicroRNAs in infectious diseases: potential diagnostic biomarkers and therapeutic targets

M Kimura, S Kothari, W Gohir… - Clinical microbiology …, 2023‏ - journals.asm.org
MicroRNAs (miRNAs) are conserved, short, non-coding RNAs that play a crucial role in the
post-transcriptional regulation of gene expression. They have been implicated in the …

MicroRNA key to angiogenesis regulation: MiRNA biology and therapy

A Tiwari, B Mukherjee, M Dixit - Current cancer drug targets, 2018‏ - ingentaconnect.com
Angiogenesis is involved in maintaining normal physiological processes like embryonic
development, wound healing, inflammation and reproduction. Pathogenesis of various …

Pathogenesis of herpes simplex keratitis: The host cell response and ocular surface sequelae to infection and inflammation

AM Lobo, AM Agelidis, D Shukla - The ocular surface, 2019‏ - Elsevier
Herpes simplex virus type 1 (HSV) keratitis is a leading cause of infectious blindness.
Clinical disease occurs variably throughout the cornea from epithelium to endothelium and …

The immunobiology of corneal HSV-1 infection and herpetic stromal keratitis

F Antony, D Kinha, A Nowińska, BT Rouse… - Clinical Microbiology …, 2024‏ - journals.asm.org
SUMMARY Human alphaherpesvirus 1 (HSV-1) is a highly successful neurotropic pathogen
that primarily infects the epithelial cells lining the orofacial mucosa. After primary lytic …

A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency

D Pan, O Flores, JL Umbach, JM Pesola, P Bentley… - Cell host & …, 2014‏ - cell.com
After infecting peripheral sites, herpes simplex virus (HSV) invades the nervous system and
initiates latent infection in sensory neurons. Establishment and maintenance of HSV latency …

Pathological processes activated by herpes simplex virus-1 (HSV-1) infection in the cornea

L Koujah, RK Suryawanshi, D Shukla - Cellular and molecular life …, 2019‏ - Springer
Herpes simplex virus type-1 (HSV-1) is a ubiquitous pathogen that infects a large majority of
the human population worldwide. It is also a leading cause of infection-related blindness in …

Pathogenesis of herpes stromal keratitis: immune inflammatory response mediated by inflammatory regulators

L Wang, R Wang, C Xu, H Zhou - Frontiers in immunology, 2020‏ - frontiersin.org
Herpes stromal keratitis (HSK) is one of the primary diseases that cause vision loss or even
blindness after herpes simplex virus (HSV)-1 infection. HSK-associated vision impairment is …

[HTML][HTML] Clinical management of herpes simplex virus keratitis

BA Labib, DGI Chigbu - Diagnostics, 2022‏ - mdpi.com
Herpes simplex virus (HSV) keratitis is one of the leading causes of blindness worldwide.
Additionally, up to 90% of the population in some countries is seropositive for HSV. HSV can …

Tear film microRNAs as potential biomarkers: A review

J Altman, G Jones, S Ahmed, S Sharma… - International journal of …, 2023‏ - mdpi.com
MicroRNAs are non-coding RNAs that serve as regulatory molecules in a variety of
pathways such as inflammation, metabolism, homeostasis, cell machinery, and …

[HTML][HTML] MicroRNA-132 with therapeutic potential in chronic wounds

X Li, D Li, A Wang, T Chu, W Lohcharoenkal… - Journal of investigative …, 2017‏ - Elsevier
Chronic wounds represent a major and rising health and economic burden worldwide.
There is a continued search toward more effective wound therapy. We found significantly …