Physiological and pathological roles for microRNAs in the immune system
Mammalian microRNAs (miRNAs) have recently been identified as important regulators of
gene expression, and they function by repressing specific target genes at the post …
gene expression, and they function by repressing specific target genes at the post …
The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease
E Mogilyansky, I Rigoutsos - Cell Death & Differentiation, 2013 - nature.com
Abstract The miR-17/92 cluster is among the best-studied microRNA clusters. Interest in the
cluster and its members has been increasing steadily and the number of publications has …
cluster and its members has been increasing steadily and the number of publications has …
MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases
R Dai, SA Ahmed - Translational Research, 2011 - Elsevier
MicroRNAs (miRNAs) are newly discovered, small, noncoding ribonucleic acids (RNAs) that
play critical roles in the regulation of host genome expression at the posttranscriptional level …
play critical roles in the regulation of host genome expression at the posttranscriptional level …
Detrimental and protective action of microglial extracellular vesicles on myelin lesions: astrocyte involvement in remyelination failure
M Lombardi, R Parolisi, F Scaroni, E Bonfanti… - Acta …, 2019 - Springer
Microglia are highly plastic immune cells which exist in a continuum of activation states. By
sha** the function of oligodendrocyte precursor cells (OPCs), the brain cells which …
sha** the function of oligodendrocyte precursor cells (OPCs), the brain cells which …
Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls
A Keller, P Leidinger, J Lange, A Borries, H Schroers… - PloS one, 2009 - journals.plos.org
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system, which is heterogenous with respect to clinical manifestations and response …
nervous system, which is heterogenous with respect to clinical manifestations and response …
Systems vaccinology
Vaccination is one of the greatest triumphs of modern medicine, yet we remain largely
ignorant of the mechanisms by which successful vaccines stimulate protective immunity …
ignorant of the mechanisms by which successful vaccines stimulate protective immunity …
Toward the blood-borne miRNome of human diseases
In a multicenter study, we determined the expression profiles of 863 microRNAs by array
analysis of 454 blood samples from human individuals with different cancers or noncancer …
analysis of 454 blood samples from human individuals with different cancers or noncancer …
Circulating microRNAs as biomarkers for disease staging in multiple sclerosis
Objective MicroRNAs (miRNAs) are single‐stranded, small noncoding RNAs that regulate
gene expression. Because they are stable in serum, they are being developed as …
gene expression. Because they are stable in serum, they are being developed as …
Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation …
E Stagakis, G Bertsias, P Verginis, M Nakou… - Annals of the …, 2011 - ard.bmj.com
Objective MicroRNAs (miRNAs) regulate the expression of genes involved in immune
activation. A study was undertaken to characterise the miRNA signature and identify novel …
activation. A study was undertaken to characterise the miRNA signature and identify novel …
Biomarkers in multiple sclerosis
Substantial effort has been made over the last six decades to identify biomarkers for multiple
sclerosis that can improve disease diagnosis, predict disease progression, and improve …
sclerosis that can improve disease diagnosis, predict disease progression, and improve …