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Bacterial persisters: molecular mechanisms and therapeutic development
H Niu, J Gu, Y Zhang - Signal transduction and targeted therapy, 2024 - nature.com
Persisters refer to genetically drug susceptible quiescent (non-growing or slow growing)
bacteria that survive in stress environments such as antibiotic exposure, acidic and …
bacteria that survive in stress environments such as antibiotic exposure, acidic and …
Tolerance and Resistance of Pseudomonas aeruginosa Biofilms to Antimicrobial Agents—How P. aeruginosa Can Escape Antibiotics
O Ciofu, T Tolker-Nielsen - Frontiers in microbiology, 2019 - frontiersin.org
Pseudomonas aeruginosa is one of the six bacterial pathogens, Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …
Recent updates on drug resistance in Mycobacterium tuberculosis
Tuberculosis (TB) along with acquired immune deficiency syndrome and malaria rank
among the top three fatal infectious diseases which pose threat to global public health …
among the top three fatal infectious diseases which pose threat to global public health …
Relationship between quorum sensing and secretion systems
Quorum sensing (QS) is a communication mechanism between bacteria that allows specific
processes to be controlled, such as biofilm formation, virulence factor expression, production …
processes to be controlled, such as biofilm formation, virulence factor expression, production …
Mechanisms of antimicrobial resistance in biofilms
Most bacteria in nature exist in aggregated communities known as biofilms, and cells within
a biofilm demonstrate major physiological changes compared to their planktonic …
a biofilm demonstrate major physiological changes compared to their planktonic …
RpoS and the bacterial general stress response
S Bouillet, TS Bauer, S Gottesman - Microbiology and Molecular …, 2024 - journals.asm.org
The general stress response (GSR) is a widespread strategy developed by bacteria to adapt
and respond to their changing environments. The GSR is induced by one or multiple …
and respond to their changing environments. The GSR is induced by one or multiple …
Intrinsic antimicrobial resistance: molecular biomaterials to combat microbial biofilms and bacterial persisters
S Barman, LB Kurnaz, R Leighton, MW Hossain… - Biomaterials, 2024 - Elsevier
The escalating rise in antimicrobial resistance (AMR) coupled with a declining arsenal of
new antibiotics is imposing serious threats to global public health. A pervasive aspect of …
new antibiotics is imposing serious threats to global public health. A pervasive aspect of …
The DNA damage inducible SOS response is a key player in the generation of bacterial persister cells and population wide tolerance
Z Podlesek, D Žgur Bertok - Frontiers in microbiology, 2020 - frontiersin.org
Population-wide tolerance and persisters enable susceptible bacterial cells to endure
hostile environments, including antimicrobial exposure. The SOS response can play a …
hostile environments, including antimicrobial exposure. The SOS response can play a …
Mechanisms of drug-induced tolerance in Mycobacterium tuberculosis
SN Goossens, SL Sampson… - Clinical microbiology …, 2020 - journals.asm.org
Successful treatment of tuberculosis (TB) can be hampered by Mycobacterium tuberculosis
populations that are temporarily able to survive antibiotic pressure in the absence of drug …
populations that are temporarily able to survive antibiotic pressure in the absence of drug …
Strategies to combat multidrug-resistant and persistent infectious diseases
Antibiotic failure is one of the most worrying health problems worldwide. We are currently
facing an international crisis with several problematic facets: new antibiotics are no longer …
facing an international crisis with several problematic facets: new antibiotics are no longer …