Research progress on the use of metformin in leukemia treatment

Q Wang, X Wei - Current Treatment Options in Oncology, 2024 - Springer
Opinion statement Metformin is a first-line drug in the clinical treatment of type 2 diabetes. Its
main molecular mechanism involves the activation of adenosine 5′-monophosphate …

A narrative review on potential applications of spanlastics for nose-to-brain delivery of therapeutically active agents

N Nadim, AA Khan, S Khan, R Parveen, J Ali - Advances in Colloid and …, 2024 - Elsevier
Spanlastics, which are commonly referred to as elastic niosomes, presents a modified
advancement in the area of colloidal system based drug delivery carriers. They are different …

[HTML][HTML] Drug repurposing for cancer treatment: A comprehensive review

AH Al Khzem, MS Gomaa, MS Alturki… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Cancer ranks among the primary contributors to global mortality. In 2022, the global
incidence of new cancer cases reached about 20 million, while the number of cancer-related …

[HTML][HTML] Fabrication of Thymoquinone and Ascorbic Acid-Loaded Spanlastics Gel for Hyperpigmentation: In Vitro Release, Cytotoxicity, and Skin Permeation Studies

A Zaid Alkilani, R Alkhaldi, HA Basheer, BI Amro… - Pharmaceutics, 2025 - mdpi.com
Background/Objectives: The demand for a safe compound for hyperpigmentation is
continuously increasing. Bioactive compounds such as thymoquinone (TQ) and ascorbic …

The potential of metformin nanoformulations for cancer prevention and therapy

SM Hejazian, P Pouya, SZ Vahed… - Journal of Drug Delivery …, 2024 - Elsevier
Metformin is a drug prescribed today because of its unique benefits in treating type 2
diabetes. Diabetes is a common disease that can occur at any age and can raise the risk of …

Single and Combinatorial Effects of Metformin and Thymoquinone in Diffuse Large B Cell Lymphoma Cells

U Glamočlija, L Mahmutović, E Bilajac… - Chemistry & …, 2024 - Wiley Online Library
Diffuse large B cell lymphoma (DLBCL) is classified into Germinal Center B‐cell (GCB) and
activated B‐cell (ABC) subgroups originating from different stages of lymphoid …