Diabetic microvascular disease: an endocrine society scientific statement
Both type 1 and type 2 diabetes adversely affect the microvasculature in multiple organs.
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …
Diabetic nephropathy–complications and treatment
AKH Lim - International journal of nephrology and renovascular …, 2014 - Taylor & Francis
Diabetic nephropathy is a significant cause of chronic kidney disease and end-stage renal
failure globally. Much research has been conducted in both basic science and clinical …
failure globally. Much research has been conducted in both basic science and clinical …
Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review
V Soleimani, PS Delghandi, SA Moallem… - Phytotherapy …, 2019 - Wiley Online Library
Milk thistle (Silybum marianum) is a medicinal plant from the Asteraceae family. Silymarin is
the major constituent of milk thistle extract and is a mixture of some flavonolignans such as …
the major constituent of milk thistle extract and is a mixture of some flavonolignans such as …
Diabetic nephropathy: is there a role for oxidative stress?
MK Sagoo, L Gnudi - Free Radical Biology and Medicine, 2018 - Elsevier
Oxidative stress has been implicated in the pathophysiology of diabetic nephropathy.
Studies in experimental animal models of diabetes strongly implicate oxidant species as a …
Studies in experimental animal models of diabetes strongly implicate oxidant species as a …
[HTML][HTML] Activation of Nrf2 signaling by natural products-can it alleviate diabetes?
M Matzinger, K Fischhuber, EH Heiss - Biotechnology advances, 2018 - Elsevier
Type 2 diabetes mellitus (DM) has reached pandemic proportions and effective prevention
strategies are wanted. Its onset is accompanied by cellular distress, the nuclear factor …
strategies are wanted. Its onset is accompanied by cellular distress, the nuclear factor …
Downregulation of tumor necrosis factor and other proinflammatory biomarkers by polyphenols
Human tumor necrosis factor (TNF), first isolated by our group as an anticancer agent, has
been now shown to be a primary mediator of inflammation. Till today 19 different members of …
been now shown to be a primary mediator of inflammation. Till today 19 different members of …
Role of silymarin in cancer treatment: facts, hypotheses, and questions
The flavonoid silymarin extracted from the seeds of Sylibum marianum is a mixture of 6
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …
Diabetic kidney disease: pathophysiology and therapeutic targets
S Toth-Manikowski, MG Atta - Journal of diabetes research, 2015 - Wiley Online Library
Diabetes is a worldwide epidemic that has led to a rise in diabetic kidney disease (DKD).
Over the past two decades, there has been significant clarification of the various pathways …
Over the past two decades, there has been significant clarification of the various pathways …
Silybum marianum (milk thistle) and its main constituent, silymarin, as a potential therapeutic plant in metabolic syndrome: A review
A Tajmohammadi, BM Razavi… - Phytotherapy …, 2018 - Wiley Online Library
Metabolic syndrome describes a complex metabolic risk factors including obesity,
hypertension, dyslipidemia, and diabetes. This syndrome is diagnosed by medical …
hypertension, dyslipidemia, and diabetes. This syndrome is diagnosed by medical …
Mechanistic insights into the pharmacological significance of silymarin
Medicinal plants are considered the reservoir of diverse therapeutic agents and have been
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …