Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …

The perpetuity of cancer prevalence at a global level calls for development of novel
therapeutic approaches with improved targetability and reduced adverse effects …

The practical application of nanoparticles (NPs) as chemotherapeutic drug delivery systems
is often hampered by issues such as poor circulation stability and targeting inefficiency …

Simple Summary Although there are various treatments for tumors, chemotherapy is still one
of the most dominant and irreplaceable treatment modalities nowadays. Unfortunately …

Multidrug resistance (MDR) of cancer is a persistent problem in chemotherapy. Scientists
have considered the overexpressed efflux transporters responsible for MDR and …

Mitochondria are essential cellular organelles, controlling multiple signalling pathways
critical for cell survival and cell death. Increasing evidence suggests that mitochondrial …

Zeolitic imidazole frameworks (ZIFs) are becoming a notable nanosystem in biomedicine
field, due to their unique properties of favorable biocompatibility, pH-responsive degradable …

The mitochondrion is a dynamic eukaryotic organelle that controls lethal and vital functions
of the cell. Being a critical center of metabolic activities and involved in many diseases …

The mitochondrion is an important intracellular organelle for drug targeting due to its key
roles and functions in cellular proliferation and death. In the last few decades, several …

One of the characteristics of cancer cells important for tumorigenesis is their metabolic
plasticity. Indeed, in various stress conditions, cancer cells can reshape their metabolic …