Persistent mucosal inflammation and microbial infection are characteristics of chronic
rhinosinusitis (CRS). Mucosal microbiota dysbiosis is found in other chronic inflammatory …

Objective Chronic sinusitis is a very common yet poorly understood medical condition with
significant morbidity. Hence, it remains an entity that is difficult to treat with unsatisfactory …

Sensory cells that specialize in transducing olfactory and gustatory stimuli are renewed
throughout life and can regenerate after injury unlike their counterparts in the mammalian …

Inflammatory diseases of the respiratory system such as rhinosinusitis, chronic obstructive
pulmonary disease, or bronchial asthma are strongly associated with overproduction and …

Background Microbes and allergens can stimulate the nasal mucosa, potentially leading to
the development of acute bacterial rhinosinusitis (ABRS). This study was designed to …

Objectives To survey normal murine sinonasal anatomy and to create a mouse model for
chronic bacterial rhinosinusitis. Design Anatomic, histologic, and pathophysiologic study …

The conservative nature of animal evolution makes animal models the ideal tool for learning
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …

Background: Although it is not proven, one factor considered important in the development
of sinusitis is allergic rhinitis. Objective: The purpose of this study was to determine whether …

This study aimed to investigate the effect of quercetin without intranasal inflammation and
oxidative stress in nasal and sinus mucosa, but also in serum, lungs and brain in a rat model …

Objective: To provide researchers with a survey atlas of normal paranasal sinus anatomy in
the mouse as well as to standardize the reporting of data within the murine nose and …