Cell-based therapies, such as adoptive immunotherapy and stem-cell therapy, have
received considerable attention as novel therapeutics in oncological research and clinical …

In recent years, the use of transplanted living cells pum** out active factors directly at the
site has proven to be an emergent technology. However a recurring impediment to rapid …

Since its first approval by the FDA in 2017, tremendous progress has been made in chimeric
antigen receptor (CAR) T cell therapy, the adoptive transfer of engineered, CAR-expressing …

Lentiviruses have been extensively used as gene delivery vectors since the mid-1990s.
Usually derived from the human immunodeficiency virus genome, they mediate efficient …

Minimally invasive delivery of “living cell factories” consisting of cells and therapeutic agents
has gained wide attention for next generation biomaterial device systems for multiple …

Chimeric antigen receptor T cell (CAR-T) therapy is a new and effective form of adoptive cell
therapy that is rapidly entering the mainstream for the treatment of CD19-positive …

The growing field of stem cell therapy is moving toward clinical trials in a variety of
applications, particularly for neurological diseases. However, this translation of cell …

Since the conception of cell microencapsulation, many scientists bet on this biotechnology
as they saw in it a promising alternative to protect transplanted cells from host …

Molecular imaging has played an important role in the noninvasive exploration of multiple
biological processes. Reporter gene imaging is a key part of molecular imaging. By …

The significant burden of resistance to conventional anticancer treatments in patients with
advanced disease has prompted the need to explore alternative therapeutic strategies. The …