Proteins and their assemblies are fundamental for living cells to function. Their complex
three-dimensional architecture and its stability are attributed to the combined effect of …

CO2-responsive materials undergo a change in chemical or physical properties in response
to the introduction or removal of CO2. The use of CO2 as a stimulus is advantageous as it is …

Abstract Knowledge of protein structure can be used to predict the phenotypic consequence
of a missense variant. Since structural coverage of the human proteome can be roughly …

Water is an essential participant in the stability, structure, dynamics, and function of proteins
and other biomolecules. Thermodynamically, changes in the aqueous environment affect …

Our goal was to gain a better understanding of the contribution of the burial of polar groups
and their hydrogen bonds to the conformational stability of proteins. We measured the …

Protein stability is a topic of major interest for the biotechnology, pharmaceutical and food
industries, in addition to being a daily consideration for academic researchers studying …

A novel method for differentiating between correctly and incorrectly determined regions of
protein structures based on characteristic atomic interactions is described. Different types of …

The goal of this article is to summarize what has been learned about the major forces
stabilizing proteins since the late 1980s when site-directed mutagenesis became possible …

We have developed an automatic algorithm STRIDE for protein secondary structure
assignment from atomic coordinates based on the combined use of hydrogen bond energy …

We have analysed the frequency with which potential hydrogen bond donors and acceptors
are satisfied in protein molecules. There are a small percentage of nitrogen or oxygen atoms …