Transition metal-mediated formation of C–N bonds is an essential synthetic methodology.
The discovery of the Chan–Lam amination provided a C–N bond forming process that was …

Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous
population of genetically unstable and highly infiltrative cells that are resistant to …

Phosphatidylinositol 3-kinases (PI3Ks) are a family of lipid kinases that phosphorylate the 3-
OH of the inositol ring of phosphoinositides, and deregulation of this pathway has …

This review covering literature reports from the beginning of this century to 2016 describes
the synthetic pathways, the antitumor activity, the structure-activity relationship and …

Lanthanum trifluoromethanesulfonate is an effective single-component catalyst for
synthesizing a variety of amides directly from esters and amines under mild conditions …

Among all heterocycles, the triazine scaffold occupies a prominent position, possessing a
broad range of biological activities. Triazine is found in many potent biologically active …

The review deals with the main catalytic methods for the C (sp 2)–N bond formation,
including Buchwald–Hartwig palladium-catalyzed amination of aryl and heteroaryl halides …

The high potential of quinazolinone containing natural products and their derivatives in
medicinal chemistry led us to discover four novel series of 53 compounds of quinazolinone …

This review summarizes recent reports on s-triazine and its respective analogs from the
medicinal chemistry angle. Due to its high reactivity and binding characteristic towards …

A novel series of triazine-benzimidazole analogs has been designed and synthesized for
their in vitro anticancer activities. Four compounds (6, 16, 17 and 20) were identified as …