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Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …
cargo comprising several populations with unique roles in biological processes. These …
Surface functionalization of exosomes for target-specific delivery and in vivo imaging & tracking: Strategies and significance
Exosomes are natural nanovesicles excreted by many cells for intercellular communication
and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic …
and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic …
Exosome theranostics: biology and translational medicine
C He, S Zheng, Y Luo, B Wang - Theranostics, 2018 - pmc.ncbi.nlm.nih.gov
Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules,
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …
Extracellular vesicles: unique intercellular delivery vehicles
Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound carriers
with complex cargoes including proteins, lipids, and nucleic acids. While the release of EVs …
with complex cargoes including proteins, lipids, and nucleic acids. While the release of EVs …
Extracellular vesicles as biomarkers and therapeutic tools: from pre-clinical to clinical applications
Simple Summary Extracellular vesicles (EVs) are membrane-bound vesicles released by all
cell types, differing in biogenesis, physical characteristics, and contents. Due to their central …
cell types, differing in biogenesis, physical characteristics, and contents. Due to their central …
Engineering hybrid exosomes by membrane fusion with liposomes
YT Sato, K Umezaki, S Sawada, S Mukai, Y Sasaki… - Scientific reports, 2016 - nature.com
Exosomes are a valuable biomaterial for the development of novel nanocarriers as
functionally advanced drug delivery systems. To control and modify the performance of …
functionally advanced drug delivery systems. To control and modify the performance of …
High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources
Extracellular vesicles (EVs), including exosomes and microvesicles (MVs), are explored for
use in diagnostics, therapeutics and drug delivery. However, little is known about the …
use in diagnostics, therapeutics and drug delivery. However, little is known about the …
Integrated isolation and quantitative analysis of exosome shuttled proteins and nucleic acids using immunocapture approaches
Clinical implementation of exosome based diagnostic and therapeutic applications is still
limited by the lack of standardized technologies that integrate efficient isolation of exosomes …
limited by the lack of standardized technologies that integrate efficient isolation of exosomes …
A comprehensive overview of exosomes as drug delivery vehicles—endogenous nanocarriers for targeted cancer therapy
Exosomes denote a class of secreted nanoparticles defined by size, surface protein and
lipid composition, and the ability to carry RNA and proteins. They are important mediators of …
lipid composition, and the ability to carry RNA and proteins. They are important mediators of …
Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets
G Szabo, F Momen-Heravi - Nature reviews Gastroenterology & …, 2017 - nature.com
Extracellular vesicles (EVs) are membranous vesicles originating from different cells in the
liver. The pathophysiological role of EVs is increasingly recognized in liver diseases …
liver. The pathophysiological role of EVs is increasingly recognized in liver diseases …