In-cell structural biology by NMR: the benefits of the atomic scale
FX Theillet - Chemical reviews, 2022 - ACS Publications
In-cell structural biology aims at extracting structural information about proteins or nucleic
acids in their native, cellular environment. This emerging field holds great promise and is …
acids in their native, cellular environment. This emerging field holds great promise and is …
In-cell NMR: Why and how?
NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …
SLIM: A short‐linked, highly redox‐stable trityl label for high‐sensitivity in‐cell EPR distance measurements
The understanding of biomolecular function is coupled to knowledge about the structure and
dynamics of these biomolecules, preferably acquired under native conditions. In this regard …
dynamics of these biomolecules, preferably acquired under native conditions. In this regard …
Molecular one‐and two‐qubit systems with very long coherence times
D Schäfter, J Wischnat, L Tesi, JA De Sousa… - Advanced …, 2023 - Wiley Online Library
General‐purpose quantum computation and quantum simulation require multi‐qubit
architectures with precisely defined, robust interqubit interactions, coupled with local …
architectures with precisely defined, robust interqubit interactions, coupled with local …
Impact of cellular crowding on protein structural dynamics investigated by EPR spectroscopy
The study of how the intracellular medium influences protein structural dynamics and protein–
protein interactions is a captivating area of research for scientists aiming to comprehend …
protein interactions is a captivating area of research for scientists aiming to comprehend …
In‐cell EPR: progress towards structural studies inside cells
Exploring the structure and dynamics of biomolecules in the context of their intracellular
environment has become the ultimate challenge for structural biology. As the cellular …
environment has become the ultimate challenge for structural biology. As the cellular …
Nanomolar Pulse Dipolar EPR Spectroscopy in Proteins: CuII–CuII and Nitroxide–Nitroxide Cases
The study of ever more complex biomolecular assemblies implicated in human health and
disease is facilitated by a suite of complementary biophysical methods. Pulse dipolar …
disease is facilitated by a suite of complementary biophysical methods. Pulse dipolar …
Pulse dipolar EPR for determining nanomolar binding affinities
Protein interaction studies often require very low concentrations and highly sensitive
biophysical methods. Here, we demonstrate that pulse dipolar electron paramagnetic …
biophysical methods. Here, we demonstrate that pulse dipolar electron paramagnetic …
[HTML][HTML] UWB DEER and RIDME distance measurements in Cu (II)–Cu (II) spin pairs
Abstract Distance determination by Electron Paramagnetic Resonance (EPR) based on
measurements of the dipolar coupling are technically challenging for electron spin systems …
measurements of the dipolar coupling are technically challenging for electron spin systems …
Hexanuclear Ln6L6 Complex Formation by Using an Unsymmetric Ligand
Multinuclear, self‐assembled lanthanide complexes present clear opportunities as sensors
and imaging agents. Despite the widely acknowledged potential of this class of …
and imaging agents. Despite the widely acknowledged potential of this class of …