Effect of the Protein Chain Conformation on the Collapse into Nanoparticles

TP Le, L Cavalcanti, JP Tellam… - …, 2024 - ACS Publications
Protein single-chain nanoparticles can outperform synthetic nanoparticles in biomedical
applications due to enhanced biocompatibility. Compared to synthetic (co) polymers, the …

Solvent Choice during Flow Assembly of Photocross-Linked Single-Chain Nanoparticles and Micelles Affects Cellular Uptake

Y Vo, R Raveendran, C Cao, RY Lai… - … Applied Materials & …, 2024 - ACS Publications
Polymeric micelles have widely been used as drug delivery carriers, and recently, single-
chain nanoparticles (SCNPs) emerged as potential, smaller-sized, alternatives. In this work …

Tadpole-like cationic single-chain nanoparticles display high cellular uptake

Y Vo, R Raveendran, C Cao, L Tian, RY Lai… - Journal of Materials …, 2024 - pubs.rsc.org
The successful delivery of nanoparticles (NPs) to cancer cells is dependent on various
factors, including particle size, shape, surface properties such as hydrophobicity …

Macromolecular Function Emerging from Intramolecular Peptide Stapling of Synthetic Polymers

H Kalmer, F Sbordone, J McMurtrie… - Macromolecular …, 2024 - Wiley Online Library
Protein function results from the precise folding of polypeptides into bespoke architectures.
Taking inspiration from nature, the field of single‐chain nanoparticles (SCNPs) …

Light-Induced Folding Control of Fluorescent and Catalytically Active Single-Chain Nanoparticles

PH Maag - 2024 - eprints.qut.edu.au
The thesis enhances the field of single-chain nanoparticles (SCNPs) by addressing key
challenges and exploring advanced applications. The research studies light-induced folding …

Peptide guiding motifs for folding polymers into protein-mimetic structures

S Farazi - 2024 - unsworks.unsw.edu.au
Folding polymers into well-defined nanostructures in aqueous solutions is critical for
mimicking the structure and functionalities of naturally occurring proteins. Peptide motifs …