Ferroptosis: mechanisms and links with diseases
Ferroptosis is an iron-dependent cell death, which is different from apoptosis, necrosis,
autophagy, and other forms of cell death. The process of ferroptotic cell death is defined by …
autophagy, and other forms of cell death. The process of ferroptotic cell death is defined by …
[HTML][HTML] The role of selenium in pathologies: an updated review
Selenium is an essential microelement required for a number of biological functions.
Selenium—and more specifically the amino acid selenocysteine—is present in at least 25 …
Selenium—and more specifically the amino acid selenocysteine—is present in at least 25 …
The essential elements of Alzheimer's disease
Treatments for Alzheimer's disease (AD) directed against the prominent amyloid plaque
neuropathology are yet to be proved effective despite many phase 3 clinical trials. There are …
neuropathology are yet to be proved effective despite many phase 3 clinical trials. There are …
Selenium and selenoproteins in health
F Zhang, X Li, Y Wei - Biomolecules, 2023 - mdpi.com
Selenium is a trace mineral that is essential for health. After being obtained from food and
taken up by the liver, selenium performs various physiological functions in the body in the …
taken up by the liver, selenium performs various physiological functions in the body in the …
Ferroptosis as a mechanism of neurodegeneration in Alzheimer's disease
Alzheimer's disease (AD) is the most prevalent form of dementia, with complex
pathophysiology that is not fully understood. While β‐amyloid plaque and neurofibrillary …
pathophysiology that is not fully understood. While β‐amyloid plaque and neurofibrillary …
Novel therapeutic approaches for Alzheimer's disease: an updated review
Alzheimer's disease (AD) is a progressive neurodegenerative disease and accounts for
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …
Does modulation of tau hyperphosphorylation represent a reasonable therapeutic strategy for Alzheimer's disease? From preclinical studies to the clinical trials
Protein kinases (PKs) have emerged as one of the most intensively investigated drug targets
in current pharmacological research, with indications ranging from oncology to …
in current pharmacological research, with indications ranging from oncology to …
[HTML][HTML] Mechanisms of ferroptosis in Alzheimer's disease and therapeutic effects of natural plant products: a review
D Zhao, K Yang, H Guo, J Zeng, S Wang, H Xu… - Biomedicine & …, 2023 - Elsevier
Neurodegenerative diseases, such as Alzheimer's disease (AD), are characterized by
massive loss of specific neurons. It is a progressive disabling, severe and fatal complex …
massive loss of specific neurons. It is a progressive disabling, severe and fatal complex …
[HTML][HTML] Metals linked with the most prevalent primary neurodegenerative dementias in the elderly: A narrative review
The ageing population has been steadily increasing worldwide, leading to a higher risk of
cognitive decline and dementia. Environmental toxicants, particularly metals, have been …
cognitive decline and dementia. Environmental toxicants, particularly metals, have been …
Assessment of the DTI‐ALPS parameter along the perivascular space in older adults at risk of dementia
CE Steward, VK Venkatraman, E Lui… - Journal of …, 2021 - Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE Recently, there has been growing interest in
the glymphatic system (the functional waste clearance pathway for the central nervous …
the glymphatic system (the functional waste clearance pathway for the central nervous …