The Alzheimer's Disease Neuroimaging Initiative in the era of Alzheimer's disease treatment: A review of ADNI studies from 2021 to 2022

DP Veitch, MW Weiner, M Miller, PS Aisen… - Alzheimer's & …, 2024 - Wiley Online Library
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) aims to improve
Alzheimer's disease (AD) clinical trials. Since 2006, ADNI has shared clinical, neuroimaging …

[HTML][HTML] 空间导航能力个体差异的多层次形成机制

张凤翔, 陈美璇, 蒲艺, 孔祥祯 - 心理科学进展, 2023 - journal.psych.ac.cn
空间导航活动时刻在我们的生活中发生, 导航能力在人群中表现出显著的个体差异,
其衰退也是阿尔兹海默症等认知障碍脑疾病的重要早期行为学表现. 以往研究考察了空间导航 …

Citalopram exposure of hESCs during neuronal differentiation identifies dysregulated genes involved in neurodevelopment and depression

M Spildrejorde, M Leithaug, A Samara… - Frontiers in Cell and …, 2024 - frontiersin.org
Selective serotonin reuptake inhibitors (SSRIs), including citalopram, are widely used
antidepressants during pregnancy. However, the effects of prenatal exposure to citalopram …

Transcriptional Responses of Different Brain Cell Types to Oxygen Decline

C Ravel-Godreuil, ER Roy, SN Puttapaka, S Li, Y Wang… - Brain Sciences, 2024 - mdpi.com
Brain hypoxia is associated with a wide range of physiological and clinical conditions.
Although oxygen is an essential constituent of maintaining brain functions, our …

Integrative cross-omics analysis identifies DNA methylation signatures associated with bilateral hippocampal volume, asymmetry and atrophy rate in the general …

D Liu, V Talevi, JF Tavares, R Wang, MA Imtiaz… - medRxiv, 2024 - medrxiv.org
The hippocampus exhibits volumetric differences between the left and right hemispheres
(LHCV and RHCV) and asymmetry, yet the molecular mechanisms underlying these …

Individual differences in spatial navigation: A multi-scale perspective

F Zhang, M Chen, Y Pu, XZ Kong - Advances in Psychological …, 2023 - journal.psych.ac.cn
Spatial navigation is an essential aspect of daily life that exhibits significant individual
differences. The decline in spatial navigation is considered a critical early behavioral …