Advanced metabolic engineering strategies for increasing artemisinin yield in Artemisia annua L.
Artemisinin, also known as 'Qinghaosu', is a chemically sesquiterpene lactone containing an
endoperoxide bridge. Due to the high activity to kill Plasmodium parasites, artemisinin and …
endoperoxide bridge. Due to the high activity to kill Plasmodium parasites, artemisinin and …
[HTML][HTML] JA-mediated transcriptional regulation of secondary metabolism in medicinal plants
S Afrin, JJ Huang, ZY Luo - Science Bulletin, 2015 - Elsevier
Plants produce a wide spectrum of secondary metabolites that play critical roles in plant-
environment interactions and against biotic and abiotic stresses. Moreover, many secondary …
environment interactions and against biotic and abiotic stresses. Moreover, many secondary …
The jasmonate‐responsive AaMYC2 transcription factor positively regulates artemisinin biosynthesis in Artemisia annua
The plant Artemisia annua is well known due to the production of artemisinin, a
sesquiterpene lactone that is widely used in malaria treatment. Phytohormones play …
sesquiterpene lactone that is widely used in malaria treatment. Phytohormones play …
GLANDULAR TRICHOME‐SPECIFIC WRKY 1 promotes artemisinin biosynthesis in Artemisia annua
Artemisinin is a type of sesquiterpene lactone well known as an antimalarial drug, and is
specifically produced in glandular trichomes of Artemisia annua. However, the regulatory …
specifically produced in glandular trichomes of Artemisia annua. However, the regulatory …
A basic leucine zipper transcription factor, AabZIP1, connects abscisic acid signaling with artemisinin biosynthesis in Artemisia annua
Artemisinin is a sesquiterpenoid especially synthesized in the Chinese herbal plant,
Artemisia annua, which is widely used in the treatment of malaria. Artemisinin accumulation …
Artemisia annua, which is widely used in the treatment of malaria. Artemisinin accumulation …
The cold-induced transcription factor bHLH112 promotes artemisinin biosynthesis indirectly via ERF1 in Artemisia annua
Basic helix-loop-helix (bHLH) proteins are the second largest family of transcription factors
(TFs) involved in developmental and physiological processes in plants. In this study, 205 …
(TFs) involved in developmental and physiological processes in plants. In this study, 205 …
Transgenic approach to increase artemisinin content in Artemisia annua L.
Artemisinin, the endoperoxide sesquiterpene lactone, is an effective antimalarial drug
isolated from the Chinese medicinal plant Artemisia annua L. Due to its effectiveness …
isolated from the Chinese medicinal plant Artemisia annua L. Due to its effectiveness …
Branch Pathway Blocking in Artemisia annua is a Useful Method for Obtaining High Yield Artemisinin
Z Lv, F Zhang, Q Pan, X Fu, W Jiang… - Plant and Cell …, 2016 - academic.oup.com
There are many biosynthetic pathways competing for the metabolic flux with the artemisinin
biosynthetic pathway in Artemisia annua L. To study the relationship between genes …
biosynthetic pathway in Artemisia annua L. To study the relationship between genes …
Overexpression of AaWRKY1 Leads to an Enhanced Content of Artemisinin in Artemisia annua
Artemisinin is an effective component of drugs against malaria. The regulation of artemisinin
biosynthesis is at the forefront of artemisinin research. Previous studies showed that …
biosynthesis is at the forefront of artemisinin research. Previous studies showed that …
Artemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of …
P Muangphrom, H Seki, EO Fukushima… - Journal of natural …, 2016 - Springer
Malaria is a worldwide disease caused by Plasmodium parasites. A sesquiterpene
endoperoxide artemisinin isolated from Artemisia annua was discovered and has been …
endoperoxide artemisinin isolated from Artemisia annua was discovered and has been …