Impact of protein corona on the biological identity of nanomedicine: understanding the fate of nanomaterials in the biological milieu

MH Akhter, H Khalilullah, M Gupta, MA Alfaleh… - Biomedicines, 2021‏ - mdpi.com
Nanoparticles (NPs) in contact with a biological medium are rapidly comprehended by a
number of protein molecules resulting in the formation of an NP–protein complex called …

Personalized protein coronas: a “key” factor at the nanobiointerface

MJ Hajipour, S Laurent, A Aghaie, F Rezaee… - Biomaterials …, 2014‏ - pubs.rsc.org
It is now well known that the primary interactions of biological entities (eg, tissues and cells)
with nanoparticles (NPs) are strongly influenced by the protein composition of the …

Electronic cigarette exposure causes vascular endothelial dysfunction due to NADPH oxidase activation and eNOS uncoupling

MA El-Mahdy, MG Ewees, MS Eid… - American Journal …, 2022‏ - journals.physiology.org
We recently reported a mouse model of chronic electronic cigarette (e-cig) exposure-
induced cardiovascular pathology, where long-term exposure to e-cig vape (ECV) induces …

Exploring oxidative modifications of tyrosine: an update on mechanisms of formation, advances in analysis and biological consequences

C Houée-Lévin, K Bobrowski, L Horakova… - Free radical …, 2015‏ - Taylor & Francis
Protein oxidation is increasingly recognised as an important modulator of biochemical
pathways controlling both physiological and pathological processes. While much attention …

Lead nitrate induces inflammation and apoptosis in rat lungs through the activation of NF-κB and AhR signaling pathways

IM Attafi, SA Bakheet, SF Ahmad, OM Belali… - … Science and Pollution …, 2022‏ - Springer
Lead (Pb) is one of the most frequent hazardous air contaminants, where the lungs are
particularly vulnerable to its toxicity. However, the Pb distribution and its impact on lung …

Aronia berry polyphenol consumption reduces plasma total and low-density lipoprotein cholesterol in former smokers without lowering biomarkers of inflammation and …

L **e, T Vance, B Kim, SG Lee, C Caceres, Y Wang… - Nutrition research, 2017‏ - Elsevier
Former smokers are at increased risk for cardiovascular disease. We hypothesized that
dietary aronia polyphenols would reduce biomarkers of cardiovascular disease risk …

Formation of a protein corona influences the biological identity of nanomaterials

D Nierenberg, AR Khaled… - Reports of Practical …, 2018‏ - journals.viamedica.pl
The development and testing of nanomaterials is an area of interest due to promising
diagnostic and therapeutic applications in the treatment of diseases like cancer or …

Magnetic levitation systems for disease diagnostics

AA Ashkarran, M Mahmoudi - Trends in Biotechnology, 2021‏ - cell.com
Magnetic levitation (MagLev) is a well-documented, robust technique for density
measurements and separations. Although the potential of MagLev as an emerging tool in …

Analysing the nanoparticle-protein corona for potential molecular target identification

CK Elechalawar, MN Hossen, L McNally… - Journal of Controlled …, 2020‏ - Elsevier
When nanoparticles are introduced into biological systems, host proteins tend to associate
on the particle surface to form a protein layer termed the “protein corona”(PC). Identifying the …