Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET): a randomised, phase 2, open …
Background The oligometastatic paradigm suggests that some patients with a limited
number of metastases might be cured if all lesions are eradicated. Evidence from …
number of metastases might be cured if all lesions are eradicated. Evidence from …
Stereotactic ablative radiotherapy for the comprehensive treatment of oligometastatic cancers: long-term results of the SABR-COMET phase II randomized trial
PURPOSE The oligometastatic paradigm hypothesizes that patients with a limited number of
metastases may achieve long-term disease control, or even cure, if all sites of disease can …
metastases may achieve long-term disease control, or even cure, if all sites of disease can …
Image guidance in radiation therapy for better cure of cancer
V Grégoire, M Guckenberger… - Molecular …, 2020 - Wiley Online Library
The key goal and main challenge of radiation therapy is the elimination of tumors without
any concurring damages of the surrounding healthy tissues and organs. Radiation doses …
any concurring damages of the surrounding healthy tissues and organs. Radiation doses …
Technology‐driven research for radiotherapy innovation
C Fiorino, M Guckenberger, M Schwarz… - Molecular …, 2020 - Wiley Online Library
Technology has a pivotal role in the continuous development of radiotherapy. The long road
toward modern 'high‐tech'radiation oncology has been studded with discoveries and …
toward modern 'high‐tech'radiation oncology has been studded with discoveries and …
Consolidative radiotherapy for limited metastatic non–small-cell lung cancer: a phase 2 randomized clinical trial
P Iyengar, Z Wardak, DE Gerber, V Tumati… - JAMA …, 2018 - jamanetwork.com
Importance Patterns-of-failure studies suggest that in metastatic non–small-cell lung cancer
(NSCLC) sites of gross disease at presentation are the first to progress when treated with …
(NSCLC) sites of gross disease at presentation are the first to progress when treated with …
[HTML][HTML] Defining oligometastatic disease from a radiation oncology perspective: An ESTRO-ASTRO consensus document
Y Lievens, M Guckenberger, D Gomez, M Hoyer… - Radiotherapy and …, 2020 - Elsevier
Background Recognizing the rapidly increasing interest and evidence in using metastasis-
directed radiotherapy (MDRT) for oligometastatic disease (OMD), ESTRO and ASTRO …
directed radiotherapy (MDRT) for oligometastatic disease (OMD), ESTRO and ASTRO …
Safety and survival rates associated with ablative stereotactic radiotherapy for patients with oligometastatic cancer: a systematic review and meta-analysis
Importance The oligometastatic paradigm postulates that patients with a limited number of
metastases can be treated with ablative local therapy to each site of disease with curative …
metastases can be treated with ablative local therapy to each site of disease with curative …
Pulmonary metastasectomy versus continued active monitoring in colorectal cancer (PulMiCC): a multicentre randomised clinical trial
T Treasure, V Farewell, F Macbeth, K Monson… - Trials, 2019 - Springer
Background Lung metastasectomy in the treatment of advanced colorectal cancer has been
widely adopted without good evidence of survival or palliative benefit. We aimed to test its …
widely adopted without good evidence of survival or palliative benefit. We aimed to test its …
Evaluation of safety of stereotactic body radiotherapy for the treatment of patients with multiple metastases: findings from the NRG-BR001 phase 1 trial
S Chmura, KA Winter, C Robinson, TM Pisansky… - JAMA …, 2021 - jamanetwork.com
Importance Stereotactic body radiotherapy (SBRT) for oligometastases is hypothesized to
improve survival and is increasingly used. Little evidence supports its safe use to treat …
improve survival and is increasingly used. Little evidence supports its safe use to treat …
Curative-intent metastasis-directed therapies for molecularly-defined oligorecurrent prostate cancer: a prospective phase II trial testing the oligometastasis hypothesis
RM Glicksman, U Metser, D Vines, J Valliant, Z Liu… - European urology, 2021 - Elsevier
Background The hypothesis of a curable oligometastatic prostate cancer (PCa) state
remains to be clinically-proven. Conventional imaging often fails to localize early …
remains to be clinically-proven. Conventional imaging often fails to localize early …