A developmental ontology for the mammalian brain based on the prosomeric model

L Puelles, M Harrison, G Paxinos, C Watson - Trends in neurosciences, 2013 - cell.com
In the past, attempts to create a hierarchical classification of brain structures (an ontology)
have been limited by the lack of adequate data on developmental processes. Recent studies …

Axonal projection patterns of the dorsal interneuron populations in the embryonic hindbrain

D Hirsch, A Kohl, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Unraveling the inner workings of neural circuits entails understanding the cellular origin and
axonal pathfinding of various neuronal groups during development. In the embryonic …

Mouse Fgf8‐Cre‐LacZ lineage analysis defines the territory of the postnatal mammalian isthmus

C Watson, T Shimogori, L Puelles - Journal of Comparative …, 2017 - Wiley Online Library
The isthmus is recognized as the most rostral segment of the hindbrain in non‐mammalian
vertebrates. In mammalian embryos, transient Fgf8 expression defines the develo** …

Large-scale characterization of cell niches in spatial atlases using bio-inspired graph learning

S Birk, I Bonafonte-Pardàs, AM Feriz, A Boxall, E Agirre… - bioRxiv, 2024 - biorxiv.org
Spatial omics holds great potential to elucidate tissue architecture by dissecting underlying
cell niches and cellular interactions. However, we lack an end-to-end computational …

Upper brainstem cholinergic neurons project to ascending and descending circuits

P Zhao, T Jiang, H Wang, X Jia, A Li, H Gong, X Li - BMC biology, 2023 - Springer
Background Based on their anatomical location, rostral projections of nuclei are classified as
ascending circuits, while caudal projections are classified as descending circuits. Upper …

The mesencephalic locomotor region sends a bilateral glutamatergic drive to hindbrain reticulospinal neurons in a tetrapod

D Ryczko, F Auclair, JM Cabelguen… - Journal of Comparative …, 2016 - Wiley Online Library
In vertebrates, stimulation of the mesencephalic locomotor region (MLR) on one side evokes
symmetrical locomotor movements on both sides. How this occurs was previously examined …

Atypical Course of the Habenulo‐Interpeduncular Tract in Chick Embryos

JL Ferran, L Puelles - Journal of Comparative Neurology, 2024 - Wiley Online Library
Classical studies of the avian diencephalon hardly mention the habenulo‐interpeduncular
tract (aka retroflex tract), although both the habenula (HB)(its origin) and the interpeduncular …

Nuclear derivatives and axonal projections originating from rhombomere 4 in the mouse hindbrain

M Di Bonito, M Studer, L Puelles - Brain Structure and Function, 2017 - Springer
The r4-derived territory is located in the pontine region of the brainstem, forming a wedge-
shaped slice that broadens from the choroidal roof to the ventral midline. R4-derived …

Two Subpopulations of Noradrenergic Neurons in the Locus Coeruleus Complex Distinguished by Expression of the Dorsal Neural Tube Marker Pax7

NW Plummer, EL Scappini, KG Smith… - Frontiers in …, 2017 - frontiersin.org
Central noradrenergic neurons, collectively defined by synthesis of the neurotransmitter
norepinephrine, are a diverse collection of cells in the hindbrain, differing in their anatomy …

Identification of proliferative progenitors associated with prominent postnatal growth of the pons

RA Lindquist, CD Guinto, JL Rodas-Rodriguez… - Nature …, 2016 - nature.com
The pons controls crucial sensorimotor and autonomic functions. In humans, it grows sixfold
postnatally and is a site of paediatric gliomas; however, the mechanisms of pontine growth …