T cell acute lymphoblastic leukaemia (T-ALL) is an aggressive haematological malignancy
derived from early T cell progenitors. In recent years genomic and transcriptomic studies …

Post-transcriptional regulation is involved in the regulation of many inflammatory genes. Zinc
finger protein 36 (ZFP36) family proteins are RNA-binding proteins involved in messenger …

Recent advances in cancer characterization have consistently revealed marked
heterogeneity, impeding the completion of integrated molecular and clinical maps for each …

Genetic alterations that activate NOTCH1 signaling and T cell transcription factors, coupled
with inactivation of the INK4/ARF tumor suppressors, are hallmarks of T-lineage acute …

Adult T cell leukemia/lymphoma (ATL) is a peripheral T cell neoplasm of largely unknown
genetic basis, associated with human T cell leukemia virus type-1 (HTLV-1) infection. Here …

Approximately half of human genes generate mRNAs with alternative 3′ untranslated
regions (3′ UTRs). Through 3′ UTR-mediated protein-protein interactions, alternative 3 …

The identity and degree of heterogeneity of glial progenitors and their contributions to brain
tumor malignancy remain elusive. By applying lineage-targeted single-cell transcriptomics …

RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …

RNA-binding proteins (RBPs) are essential for the development and function of the immune
system. They interact dynamically with RNA to control its biogenesis and turnover by …

RNA binding proteins are important regulators of T cell activation, proliferation, and cytokine
production. The zinc finger protein 36 (ZFP36) family genes (Zfp36, Zfp36l1, and Zfp36l2) …