Imidazole as a promising medicinal scaffold: current status and future direction

SS Alghamdi, RS Suliman, K Almutairi… - Drug Design …, 2021 - Taylor & Francis
Various imidazole-containing compounds have been tested for their medical usefulness in
clinical trials for several disease conditions. The rapid expansion of imidazole-based …

Ionic liquids in pharmaceutical industry: A systematic review on applications and future perspectives

W Zhuang, K Hachem, D Bokov, MJ Ansari… - Journal of Molecular …, 2022 - Elsevier
Ionic liquids (ILs) have demonstrated incredible potential of application in various industries
such as pharmaceutics. Appropriate utilization of ILs in the pharmaceutical industry can be a …

Green Synthesis of Zinc Oxide Nanoparticles Using Aqueous Extract of Deverra tortuosa and their Cytotoxic Activities

YA Selim, MA Azb, I Ragab, M HM Abd El-Azim - Scientific reports, 2020 - nature.com
In recent years, there is a growing interest towards the green synthesis of metal
nanoparticles, particularly from plants; however, yet no published study on the synthesis of …

Green synthesis of nanoparticles and their biomedical applications: a review

N Shreyash, S Bajpai, MA Khan, Y Vijay… - ACS Applied Nano …, 2021 - ACS Publications
In the arena of material sciences, one of the burning topics for research has been
biogenically synthesizing nanoparticles (NPs) from plant derivatives and studying their …

TranSynergy: Mechanism-driven interpretable deep neural network for the synergistic prediction and pathway deconvolution of drug combinations

Q Liu, L **e - PLoS computational biology, 2021 - journals.plos.org
Drug combinations have demonstrated great potential in cancer treatments. They alleviate
drug resistance and improve therapeutic efficacy. The fast-growing number of anti-cancer …

Zinc oxide nanoparticles promise anticancer and antibacterial activity in ovarian cancer

AB Mousa, R Moawad, Y Abdallah… - Pharmaceutical …, 2023 - Springer
Background Ovarian cancer is the most lethal cancer in gynaecology. Surgery,
chemotherapy, and radiotherapy are the most often used cancer-fighting strategies. Post …

Chiral 1, 1-diaryl compounds as important pharmacophores

D Ameen, TJ Snape - MedChemComm, 2013 - pubs.rsc.org
Compounds containing a 1, 1-diaryl motif are numerous, and compounds of this type have
found use as catalysts and molecular building blocks, however, this review focusses solely …

Pharmacological management of ionizing radiation injuries: current and prospective agents and targeted organ systems

VK Singh, TM Seed - Expert opinion on pharmacotherapy, 2020 - Taylor & Francis
Introduction: There is a limited array of currently available medicinals that are useful for
either the prevention, mitigation or treatment of bodily injuries arising from ionizing radiation …

Saponins of Agave: Chemistry and bioactivity

J Sidana, B Singh, OP Sharma - Phytochemistry, 2016 - Elsevier
The genus Agave comprises more than 400 species with geographical presence in the
tropical and sub-tropical regions of the world. These plants have a rich history of folkloric use …

Saponins as cytotoxic agents: An update (2010–2021). Part II—Triterpene saponins

I Podolak, K Grabowska, D Sobolewska… - Phytochemistry …, 2023 - Springer
Saponins make up an important group of natural glycosidic compounds which are
distinguished by triterpene or steroidal aglycone. Although widely distributed in terrestrial …