Sex differences in hippocampal cognition and neurogenesis

S Yagi, LAM Galea - Neuropsychopharmacology, 2019‏ - nature.com
Sex differences are reported in hippocampal plasticity, cognition, and in a number of
disorders that target the integrity of the hippocampus. For example, meta-analyses reveal …

Sex differences in cognitive impairment and Alzheimer's disease

R Li, M Singh - Frontiers in neuroendocrinology, 2014‏ - Elsevier
Studies have shown differences in specific cognitive ability domains and risk of Alzheimer's
disease between the men and women at later age. However it is important to know that sex …

Structural plasticity of the hippocampus in response to estrogens in female rodents

PAS Sheppard, E Choleris, LAM Galea - Molecular brain, 2019‏ - Springer
It is well established that estrogens affect neuroplasticity in a number of brain regions. In
particular, estrogens modulate and mediate spine and synapse formation as well as …

Sex hormones and cognition: neuroendocrine influences on memory and learning.

DK Hamson, MM Roes, LAM Galea - 2016‏ - open.library.ubc.ca
Sex differences in neurological disease extend from incidence, severity, progression and
symptoms and may ultimately influence treatment. Cognitive disturbances are frequent in …

Sex hormones and adult hippocampal neurogenesis: Regulation, implications, and potential mechanisms

R Mahmoud, SR Wainwright, LAM Galea - Frontiers in neuroendocrinology, 2016‏ - Elsevier
Neurogenesis within the adult hippocampus is modulated by endogenous and exogenous
factors. Here, we review the role of sex hormones in the regulation of adult hippocampal …

Hippocampal learning, memory, and neurogenesis: Effects of sex and estrogens across the lifespan in adults

P Duarte-Guterman, S Yagi, C Chow, LAM Galea - Hormones and behavior, 2015‏ - Elsevier
This article is part of a Special Issue “Estradiol and Cognition”. There are sex differences in
hippocampus-dependent cognition and neurogenesis suggesting that sex hormones are …

Why estrogens matter for behavior and brain health

LAM Galea, KM Frick, E Hampson, F Sohrabji… - Neuroscience & …, 2017‏ - Elsevier
Abstract The National Institutes of Health (NIH) has required the inclusion of women in
clinical studies since 1993, which has enhanced our understanding of how biological sex …

Sex, hormones and neurogenesis in the hippocampus: hormonal modulation of neurogenesis and potential functional implications

LAM Galea, SR Wainwright, MM Roes… - Journal of …, 2013‏ - Wiley Online Library
The hippocampus is an area of the brain that undergoes dramatic plasticity in response to
experience and hormone exposure. The hippocampus retains the ability to produce new …

The effects of hormones and physical exercise on hippocampal structural plasticity

J Triviño-Paredes, AR Patten, J Gil-Mohapel… - Frontiers in …, 2016‏ - Elsevier
The hippocampus plays an integral role in certain aspects of cognition. Hippocampal
structural plasticity and in particular adult hippocampal neurogenesis can be influenced by …

The effects of extrinsic and intrinsic factors on neurogenesis

M Jiang, SE Jang, L Zeng - Cells, 2023‏ - mdpi.com
In the mammalian brain, neurogenesis is maintained throughout adulthood primarily in two
typical niches, the subgranular zone (SGZ) of the dentate gyrus and the subventricular zone …