[HTML][HTML] Beyond CFD: Emerging methodologies for predictive simulation in cardiovascular health and disease

EL Schwarz, L Pegolotti, MR Pfaller… - Biophysics Reviews, 2023 - pubs.aip.org
Physics-based computational models of the cardiovascular system are increasingly used to
simulate hemodynamics, tissue mechanics, and physiology in evolving healthy and …

Learning reduced-order models for cardiovascular simulations with graph neural networks

L Pegolotti, MR Pfaller, NL Rubio, K Ding… - Computers in Biology …, 2024 - Elsevier
Reduced-order models based on physics are a popular choice in cardiovascular modeling
due to their efficiency, but they may experience loss in accuracy when working with …

Automated generation of 0D and 1D reduced‐order models of patient‐specific blood flow

MR Pfaller, J Pham, A Verma, L Pegolotti… - … journal for numerical …, 2022 - Wiley Online Library
Abstract Three‐dimensional (3D) cardiovascular fluid dynamics simulations typically require
hours to days of computing time on a high‐performance computing cluster. One …

On the periodicity of cardiovascular fluid dynamics simulations

MR Pfaller, J Pham, NM Wilson, DW Parker… - Annals of biomedical …, 2021 - Springer
Three-dimensional cardiovascular fluid dynamics simulations typically require computation
of several cardiac cycles before they reach a periodic solution, rendering them …

Modeling blood flow in networks of viscoelastic vessels with the 1-D augmented fluid–structure interaction system

F Piccioli, G Bertaglia, A Valiani, V Caleffi - Journal of Computational …, 2022 - Elsevier
A noteworthy aspect in blood flow modeling is the definition of the mechanical interaction
between the fluid flow and the biological structure that contains it, namely the vessel wall …

Uncertainty quantification of viscoelastic parameters in arterial hemodynamics with the a-FSI blood flow model

G Bertaglia, V Caleffi, L Pareschi, A Valiani - Journal of Computational …, 2021 - Elsevier
This work aims at identifying and quantifying uncertainties related to elastic and viscoelastic
parameters, which characterize the arterial wall behavior, in one-dimensional modeling of …

[HTML][HTML] A semi-implicit finite volume scheme for blood flow in elastic and viscoelastic vessels

A Lucca, S Busto, LO Müller, EF Toro… - Journal of Computational …, 2023 - Elsevier
A novel staggered semi-implicit finite volume method for the simulation of one-dimensional
blood flow in networks of elastic and viscoelastic vessels is proposed. The one-dimensional …

A method of parameter estimation for cardiovascular hemodynamics based on deep learning and its application to personalize a reduced‐order model

Y Zhou, Y He, J Wu, C Cui, M Chen… - International Journal for …, 2022 - Wiley Online Library
Precise model personalization is a key step towards the application of cardiovascular
physical models. In this manuscript, we propose to use deep learning (DL) to solve the …

Determining clinically-viable biomarkers for ischaemic stroke through a mechanistic and machine learning approach

I Benemerito, AP Narata, A Narracott… - Annals of Biomedical …, 2022 - Springer
Assessment of distal cerebral perfusion after ischaemic stroke is currently only possible
through expensive and time-consuming imaging procedures which require the injection of a …

The effect of cardiac properties on arterial pulse waves: An in‐silico study

F Piccioli, A Valiani, J Alastruey… - International Journal for …, 2022 - Wiley Online Library
This study investigated the effects of cardiac properties variability on arterial pulse wave
morphology using blood flow modelling and pulse wave analysis. A lumped‐parameter …