Strains of uropathogenic E. coli (UPEC) are the primary cause of urinary tract infections,
including both cystitis and pyelonephritis. These bacteria have evolved a multitude of …

Integrins are heterodimeric glycoproteins crucial to the physiology and pathology of many
biological functions. As adhesion molecules, they mediate immune cell trafficking, migration …

Uropathogenic Escherichia coli (UPEC), the primary causative agent of urinary tract
infections, typically express filamentous adhesive organelles called type 1 pili that mediate …

The multifunctional human glycoprotein vitronectin (Vn) plays a significant role in cell
migration, tissue repair and regulation of membrane attack complex (MAC) formation. It also …

The ability of bacterial pathogens to invade host cells can have profound effects on the
establishment, persistence, and propagation of infections. By entering host cells and …

The gut represents an important site of colonization of the commensal bacterium
Streptococcus agalactiae (group B Streptococcus or GBS), which can also behave as a …

Background Plasminogen activator inhibitor type 1 (PAI-1) is the primary inhibitor of
urokinase type plasminogen activators (uPA) and tissue type plasminogen activators (tPA) …

Mycoplasma hyorhinis may cause systemic inflammation of pigs, typically polyserositis and
arthritis, and is also associated with several types of human cancer. However, the …

Shiga toxin-producing Escherichia coli (STEC) are zoonotic Gram-negative bacteria. While
raw milk cheese consumption is healthful, contamination with pathogens such as STEC can …

Integrins are transmembrane proteins that are most typically thought of as integrating
adhesion to the extracellular matrix with intracellular signaling and cell regulation …