Primary and metastatic peritoneal surface malignancies
Peritoneal surface malignancies comprise a heterogeneous group of primary tumours,
including peritoneal mesothelioma, and peritoneal metastases of other tumours, including …
including peritoneal mesothelioma, and peritoneal metastases of other tumours, including …
[HTML][HTML] PARP inhibitors: clinical limitations and recent attempts to overcome them
D Kim, HJ Nam - International Journal of Molecular Sciences, 2022 - mdpi.com
PARP inhibitors are the first clinically approved drugs that were developed based on
synthetic lethality. PARP inhibitors have shown promising outcomes since their clinical …
synthetic lethality. PARP inhibitors have shown promising outcomes since their clinical …
Genetic/familial high-risk assessment: breast, ovarian, and pancreatic, version 2.2021, NCCN clinical practice guidelines in oncology
MB Daly, T Pal, MP Berry, SS Buys, P Dickson… - Journal of the National …, 2021 - jnccn.org
The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and
Pancreatic focus primarily on assessment of pathogenic or likely pathogenic variants …
Pancreatic focus primarily on assessment of pathogenic or likely pathogenic variants …
High grade serous ovarian carcinomas originate in the fallopian tube
SI Labidi-Galy, E Papp, D Hallberg, N Niknafs… - Nature …, 2017 - nature.com
High-grade serous ovarian carcinoma (HGSOC) is the most frequent type of ovarian cancer
and has a poor outcome. It has been proposed that fallopian tube cancers may be …
and has a poor outcome. It has been proposed that fallopian tube cancers may be …
Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer: US Preventive Services Task Force recommendation statement
Importance Potentially harmful mutations of the breast cancer susceptibility 1 and 2 genes
(BRCA1/2) are associated with increased risk for breast, ovarian, fallopian tube, and …
(BRCA1/2) are associated with increased risk for breast, ovarian, fallopian tube, and …
Consensus guidelines on genetictesting for hereditary breast cancer from the American Society of Breast Surgeons
ER Manahan, HM Kuerer, M Sebastian… - Annals of surgical …, 2019 - Springer
Background The purpose of this consensus guideline is to outline recommendations for
genetic testing that medical professionals can use to assess hereditary risk for breast …
genetic testing that medical professionals can use to assess hereditary risk for breast …
The ErbB/HER family of protein-tyrosine kinases and cancer
R Roskoski Jr - Pharmacological research, 2014 - Elsevier
The human epidermal growth factor receptor (EGFR) family consists of four members that
belong to the ErbB lineage of proteins (ErbB1–4). These receptors consist of a glycosylated …
belong to the ErbB lineage of proteins (ErbB1–4). These receptors consist of a glycosylated …
[HTML][HTML] Genetics of breast cancer: a topic in evolution
S Shiovitz, LA Korde - Annals of Oncology, 2015 - Elsevier
ABSTRACT A hereditary predisposition to breast cancer significantly influences screening
and follow-up recommendations for high-risk women. However, in patients with a suggestive …
and follow-up recommendations for high-risk women. However, in patients with a suggestive …
Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations
The prevalence and spectrum of germline mutations in BRCA1 and BRCA2 have been
reported in single populations, with the majority of reports focused on White in Europe and …
reported in single populations, with the majority of reports focused on White in Europe and …
Cell origins of high-grade serous ovarian cancer
J Kim, EY Park, O Kim, JM Schilder, DM Coffey… - Cancers, 2018 - mdpi.com
High-grade serous ovarian cancer, also known as high-grade serous carcinoma (HGSC), is
the most common and deadliest type of ovarian cancer. HGSC appears to arise from the …
the most common and deadliest type of ovarian cancer. HGSC appears to arise from the …