The structure of the brain is constantly changing from birth throughout the lifetime, meaning
that normal aging, free from dementia, is associated with structural brain changes. This …

Both normal aging and Alzheimer's disease (AD) are associated with changes in cognition,
grey and white matter volume, white matter integrity, neural activation, functional …

Magnetic resonance imaging volumetry studies report inverted U-patterns with increasing
white-matter (WM) volume into middle age suggesting protracted WM maturation compared …

Currently, no reliable predictors of cognitive impairment in Parkinson's disease exist. We
hypothesized that microstructural changes at grey matter T1-weighted MRI and diffusion …

Though mild cognitive impairment is an intermediate clinical state between healthy aging
and Alzheimer's disease (AD), there are very few whole-brain voxel-wise diffusion MRI …

Normal ageing is associated with gradual brain atrophy. Determining spatial and temporal
patterns of change can help shed light on underlying mechanisms. Neuroimaging provides …

Purpose: To test patient acceptance and reproducibility of the 3D magnetic resonance
elastography (MRE) brain exam using a soft vibration source, and to determine if MRE could …

We reviewed case-control studies of diffusion tensor imaging (DTI) in patients with
Alzheimer's dementia (AD) and mild cognitive impairment (MCI), in order to establish the …

Alzheimer's disease (AD) has traditionally been regarded as a disease of the gray matter
(GM). However, the advent of diffusion tensor imaging (DTI) has contributed to new …

Purpose To explore the regional patterns of white matter (WM) tract damage in (a) patients
with probable Alzheimer disease (AD) and (b) patients with amnestic mild cognitive …