The β-thymosins are a family of highly conserved polar 5 kDa peptides originally thought to
be thymic hormones. About 10 years ago, thymosin β4 as well as other members of this …

Here, we review the biochemical and molecular properties of thymosin β 4 (Tβ 4), the major
actin-sequestering molecule in eukaryotic cells, and its key role in dermal-and corneal …

Cardiac failure has a principal underlying aetiology of ischaemic damage arising from
vascular insufficiency. Molecules that regulate collateral growth in the ischaemic heart also …

Angiotensin I-converting enzyme (ACE) has two homologous active NH2-and COOH-
terminal domains and displays activity toward a broad range of substrates. The tetrapeptide …

Published studies have described a number of physiological properties and cellular
functions of thymosin β4 (Tβ4), the major G‐actin‐sequestering molecule in mammalian …

The interaction of G-actin with thymosin beta 4 (T beta 4), the major G-actin-sequestering
protein in motile and proliferating cells, has been analyzed in vitro. T beta 4 is found to have …

The degradation of N-Ac-Ser-Asp-Lys-Pro (AcSDKP), a negative regulator controlling the
proliferation of the haematopoietic stem cell, by enzymes present in human plasma, has …

Proteomic surveys with top-down platforms are today revealing thousands of naturally
occurring fragments of bigger proteins. Some of them have not functional meaning because …

Cardiovascular diseases (CVDs) represent∼ 31% of all global deaths, and hypertension
alone accounts for∼ 50% of these cases. Inflammation and subsequent fibrosis in heart …

The studies on thymosins were initiated in 1965, when the group of A. White searched for
thymic factors responsible for the physiological functions of thymus. To restore thymic …