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The evolution and ecology of benign tumors
Tumors are usually classified into two main categories–benign or malignant, with much
more attention being devoted to the second category given that they are usually associated …
more attention being devoted to the second category given that they are usually associated …
[HTML][HTML] Thioredoxin reductase selenoproteins from different organisms as potential drug targets for treatment of human diseases
R Gencheva, Q Cheng, ESJ Arner - Free Radical Biology and Medicine, 2022 - Elsevier
Human thioredoxin reductase (TrxR) is a selenoprotein with a central role in cellular redox
homeostasis, utilizing a highly reactive and solvent-exposed selenocysteine (Sec) residue in …
homeostasis, utilizing a highly reactive and solvent-exposed selenocysteine (Sec) residue in …
Behavioral biology of Toxoplasma gondii infection
Toxoplasma gondii is a protozoan parasite with a complex life cycle and a cosmopolitan
host range. The asexual part of its life cycle can be perpetually sustained in a variety of …
host range. The asexual part of its life cycle can be perpetually sustained in a variety of …
Drug repurposing and relabeling for cancer therapy: Emerging benzimidazole antihelminthics with potent anticancer effects
Origin of drug and radio-refractory clones, cancer stem-like cells, and rapid angiogenesis
and metastasis are among the primary concerns that limit the efficacy of anticancer …
and metastasis are among the primary concerns that limit the efficacy of anticancer …
A framework for how environment contributes to cancer risk
Evolutionary theory explains why metazoan species are largely protected against the
negative fitness effects of cancers. Nevertheless, cancer is often observed at high incidence …
negative fitness effects of cancers. Nevertheless, cancer is often observed at high incidence …
The ecology and evolution of wildlife cancers: Applications for management and conservation
Ecological and evolutionary concepts have been widely adopted to understand host–
pathogen dynamics, and more recently, integrated into wildlife disease management …
pathogen dynamics, and more recently, integrated into wildlife disease management …
The complex effects of modern oncogenic environments on the fitness, evolution and conservation of wildlife species
Growing evidence indicates that human activities are causing cancer rates to rise in both
human and wildlife populations. This is due to the inability of ancestral anti‐cancer defences …
human and wildlife populations. This is due to the inability of ancestral anti‐cancer defences …
Genetic diversity, inbreeding and cancer
Genetic diversity is essential for adaptive capacities, providing organisms with the potential
of successfully responding to intrinsic and extrinsic challenges. Although a clear reciprocal …
of successfully responding to intrinsic and extrinsic challenges. Although a clear reciprocal …
Traits of a mussel transmissible cancer are reminiscent of a parasitic life style
Some cancers have evolved the ability to spread from host to host by transmission of
cancerous cells. These rare biological entities can be considered parasites with a host …
cancerous cells. These rare biological entities can be considered parasites with a host …
Infectious disease and sickness behaviour: tumour progression affects interaction patterns and social network structure in wild Tasmanian devils
Infectious diseases, including transmissible cancers, can have a broad range of impacts on
host behaviour, particularly in the latter stages of disease progression. However, the …
host behaviour, particularly in the latter stages of disease progression. However, the …