Unraveling the molecular pathogenesis of Type 2 Diabetes and its impact on female infertility: A bioinformatics and systems biology approach
Type 2 diabetes mellitus (T2D) has been linked with female infertility (FI). Nevertheless, our
understanding of the molecular hallmarks and underlying mechanisms remains elusive. This …
understanding of the molecular hallmarks and underlying mechanisms remains elusive. This …
Integrated bioinformatics and statistical approach to identify the common molecular mechanisms of obesity that are linked to the development of two psychiatric …
Obesity is a chronic multifactorial disease characterized by the accumulation of body fat and
serves as a gateway to a number of metabolic-related diseases. Epidemiologic data indicate …
serves as a gateway to a number of metabolic-related diseases. Epidemiologic data indicate …
A Comprehensive Bioinformatics Approach to Identify Molecular Signatures and Key Pathways for the Huntington Disease
TM Meem, U Khan, MBR Mredul… - … and Biology Insights, 2023 - journals.sagepub.com
Huntington disease (HD) is a degenerative brain disease caused by the expansion of CAG
(cytosine-adenine-guanine) repeats, which is inherited as a dominant trait and progressively …
(cytosine-adenine-guanine) repeats, which is inherited as a dominant trait and progressively …
Bioinformatics and system biology techniques to determine biomolecular signatures and pathways of prion disorder
Prion disorder (PD) is caused by misfolding and the formation of clumps of proteins in the
brain, notably Prion proteins resulting in a steady decrease in brain function. Early detection …
brain, notably Prion proteins resulting in a steady decrease in brain function. Early detection …
[HTML][HTML] Bioinformatics and system biology approaches to identify molecular pathogenesis of polycystic ovarian syndrome, type 2 diabetes, obesity, and …
Female infertility may be caused by several medical conditions and environmental factors
that induce fallopian tube damage or hormonal difficulties. Several metabolic comorbidities …
that induce fallopian tube damage or hormonal difficulties. Several metabolic comorbidities …
Identification of molecular targets and small drug candidates for Huntington's disease via bioinformatics and a network‐based screening approach
Huntington's disease (HD) is a gradually severe neurodegenerative ailment characterised
by an increase of a specific trinucleotide repeat sequence (cytosine–adenine–guanine …
by an increase of a specific trinucleotide repeat sequence (cytosine–adenine–guanine …
Effect of antipsychotics on the focal adhesion pathway
B Panizzutti, CC Bortolasci, B Spolding… - The World Journal of …, 2025 - Taylor & Francis
Focal adhesions and their dynamic nature are essential for various physiological processes,
including the formation of neurites, synaptic function and plasticity. Alterations in these …
including the formation of neurites, synaptic function and plasticity. Alterations in these …
Proteomic and bioinformatic tools to identify potential hub proteins in the audiogenic seizure-prone hamster GASH/Sal
The GASH/Sal (Genetic Audiogenic Seizure Hamster, Salamanca) is a model of audiogenic
seizures with the epileptogenic focus localized in the inferior colliculus (IC). The sound …
seizures with the epileptogenic focus localized in the inferior colliculus (IC). The sound …
Drugging the Histone Acetyltransferase EP300 Modulates Alternative Splicing at Schizophrenia Risk Genes
S Malay - 2024 - scholarscompass.vcu.edu
Purpose. We will evaluate the effects of drugging the epigenetic histone acetyltransferase
(HAT) enzyme p300, encoded by the schizophrenia risk gene EP300, on genome-wide …
(HAT) enzyme p300, encoded by the schizophrenia risk gene EP300, on genome-wide …