An understanding of mechanism-based approaches for 1, 3, 4-oxadiazole scaffolds as cytotoxic agents and enzyme inhibitors
The world's health system is plagued by cancer and a worldwide effort is underway to find
new drugs to treat cancer. There has been a significant improvement in understanding the …
new drugs to treat cancer. There has been a significant improvement in understanding the …
A review exploring therapeutic worth of 1, 3, 4-oxadiazole tailored compounds
1, 3, 4-Oxadiazole, a five-membered aromatic ring can be seen in a number of synthetic
molecules. The peculiar structural feature of 1, 3, 4-oxadiazole ring with pyridine type of …
molecules. The peculiar structural feature of 1, 3, 4-oxadiazole ring with pyridine type of …
Updates on synthesis and biological activities of 1, 3, 4-oxadiazole: A review
The new era of heterocyclic moieties which are developed in the decades plays a very
important role in the treatment of various diseases. Among them are 1, 3, 4-oxadiazoles, a …
important role in the treatment of various diseases. Among them are 1, 3, 4-oxadiazoles, a …
Synthesis, characterization and corrosion inhibition potential of oxadiazole derivatives for mild steel in 1M HCl: electrochemical and computational studies
Though, there is an availability of good collection of synthesized structures that are applied
to combat corrosion, still a continued challenge of the problem provokes the modern …
to combat corrosion, still a continued challenge of the problem provokes the modern …
Synthesis of novel 2, 5-disubstituted-1, 3, 4-thiadiazoles clubbed 1, 2, 4-triazole, 1, 3, 4-thiadiazole, 1, 3, 4-oxadiazole and/or Schiff base as potential antimicrobial and …
In the present study, a new series of 2, 5-disubstituted-1, 3, 4-thiadiazole tethered 1, 2, 4-
triazole, 1, 3, 4-thiadiazole, 1, 3, 4-oxadiazole and Schiff base derivatives were synthesized …
triazole, 1, 3, 4-thiadiazole, 1, 3, 4-oxadiazole and Schiff base derivatives were synthesized …
[PDF][PDF] Anticancer activity and In-Silico ADMET analysis of malvastrum coromandelianum
A Yadav, S Mohite - International Journal of Pharma Sciences and …, 2020 - ijpsr.info
Breast cancer is the world's leading cause of cancer death and the most common cancer
among women. There is significant variation in survival rates worldwide for breast cancer …
among women. There is significant variation in survival rates worldwide for breast cancer …
In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide
AF Kassem, GO Moustafa, ES Nossier… - Journal of Enzyme …, 2019 - Taylor & Francis
Abstract A series of N1, N3-bis (1-oxopropan-2-yl) isophthalamide-based derivatives 4–16
were prepared and their structures were confirmed by different spectral tools. The cytotoxic …
were prepared and their structures were confirmed by different spectral tools. The cytotoxic …
Optimization of Pharmacophore of Novel Hybrid Nucleus of 1,3,4- oxadiazole-chalcone using Literature Findings and In silico Approach as EGFR Inhibitor
SM Patil, SV Bhandari - Letters in Drug Design & Discovery, 2023 - benthamdirect.com
Background: Cancer is a leading cause of death worldwide. EGFR is one of the important
targets considered for current chemotherapeutic agents. The problem of drug resistance can …
targets considered for current chemotherapeutic agents. The problem of drug resistance can …
Synthesis, cytotoxic evaluation, and molecular docking studies of some new 1, 3, 4-oxadiazole-based compounds
F Hassanzadeh, E Jafari, M Zarabi… - Research in …, 2020 - journals.lww.com
Background and purpose: Oxadiazole-derived compounds have been shown to have a wide
range of pharmacological activities. 2, 5-Disubstituted 1, 3, 4-oxadiazole derivatives have …
range of pharmacological activities. 2, 5-Disubstituted 1, 3, 4-oxadiazole derivatives have …
[PDF][PDF] Biological aspects of 1, 3, 4-oxadiazole derivatives
S Kavitha, S Gnanavel, K Kannan - Asian J Pharm Clin Res, 2014 - core.ac.uk
Heterocyclic compounds analog have attracted wide attention due to their useful biological
properties. Among them, 1, 3, 4-oxadiazoles have exhibited a wide range of biological …
properties. Among them, 1, 3, 4-oxadiazoles have exhibited a wide range of biological …