Tubular reabsorption of filtered sodium is quantitatively the main contribution of kidneys to
salt and water homeostasis. The transcellular reabsorption of sodium proceeds by a two …

▪ Abstract The kidney regulates sodium metabolism with extraordinary precision and
sensitivity. This is accomplished by an intricate interaction between signals from extrarenal …

BACKGROUND: Worsening renal function (WRF) and hypokalemia related to diuretic use
for acute decompensated heart failure (ADHF) are common and associated with poor …

Dopamine has been recognized as an important modulator of central as well as peripheral
physiologic functions in both humans and animals. Dopamine receptors have been …

All of the components of a complete dopamine system are present within the kidney, where
dopamine acts as a paracrine substance in the control of sodium excretion. Dopamine …

Dopamine has been widely used in pediatric and neonatal intensive care for the treatment of
hypotension or oliguria in sick preterm 1-6 and term neonates 2, 7 and in children, s …

Dopamine is an important regulator of systemic blood pressure via multiple mechanisms. It
affects fluid and electrolyte balance by its actions on renal hemodynamics and epithelial ion …

During the past decade, it has become evident that dopamine plays an important role in the
regulation of renal function and blood pressure. Dopamine exerts its actions via a class of …

Inhibition of Na+, K+-ATPase activity by dopamine is an important mechanism by which
renal tubules modulate urine sodium excretion during a high salt diet. However, the …

In this study, several lines of evidence are provided to show that Na+, K+-ATPase activity
exerts vital roles in normal brain development and function and that loss of enzyme activity is …