Local delivery of macromolecules to treat diseases associated with the colon
Current treatments for intestinal diseases including inflammatory bowel diseases, irritable
bowel syndrome, and colonic bacterial infections are typically small molecule oral dosage …
bowel syndrome, and colonic bacterial infections are typically small molecule oral dosage …
Efficacy of teduglutide for parenteral support reduction in patients with short bowel syndrome: a systematic review and meta-analysis
F Bioletto, C D'Eusebio, FD Merlo, U Aimasso… - Nutrients, 2022 - mdpi.com
Teduglutide has been described as an effective treatment for parenteral support (PS)
reduction in patients with short bowel syndrome (SBS). However, a quantitative summary of …
reduction in patients with short bowel syndrome (SBS). However, a quantitative summary of …
Engineering transplantable jejunal mucosal grafts using patient-derived organoids from children with intestinal failure
Intestinal failure, following extensive anatomical or functional loss of small intestine, has
debilitating long-term consequences for children. The priority of patient care is to increase …
debilitating long-term consequences for children. The priority of patient care is to increase …
ESPEN guideline on chronic intestinal failure in adults–Update 2023
L Pironi, C Cuerda, PB Jeppesen, F Joly, C Jonkers… - Clinical Nutrition, 2023 - Elsevier
Background & aims In 2016, ESPEN published the guideline for Chronic Intestinal Failure
(CIF) in adults. An updated version of ESPEN guidelines on CIF due to benign disease in …
(CIF) in adults. An updated version of ESPEN guidelines on CIF due to benign disease in …
Safety and efficacy of teduglutide in pediatric patients with intestinal failure due to short bowel syndrome: a 24‐week, phase III study
SA Kocoshis, RJ Merritt, S Hill… - Journal of Parenteral …, 2020 - Wiley Online Library
Background This study evaluated the safety and efficacy of teduglutide in pediatric patients
with short bowel syndrome–associated intestinal failure (SBS‐IF). Methods A 24‐week …
with short bowel syndrome–associated intestinal failure (SBS‐IF). Methods A 24‐week …
Trends in pediatric intestinal failure: a multicenter, multinational study
D Gattini, AJ Roberts, PW Wales, SV Beath… - The Journal of …, 2021 - Elsevier
Objectives To assess the natural history and outcomes of children with intestinal failure in a
large, multicenter, geographically diverse contemporary cohort (2010-2015) from 6 pediatric …
large, multicenter, geographically diverse contemporary cohort (2010-2015) from 6 pediatric …
Therapeutic potential of GLP-2 analogs in gastrointestinal disorders: current knowledge, nutritional aspects, and future perspectives
D Kounatidis, NG Vallianou, D Tsilingiris… - Current Nutrition …, 2022 - Springer
Abstract Purpose of Review Although Glucagon-like peptide (GLP)-1 receptor agonists have
been used for almost two decades in the treatment of diabetes mellitus type 2 and, lately, in …
been used for almost two decades in the treatment of diabetes mellitus type 2 and, lately, in …
Experience with teduglutide in pediatric short bowel syndrome: first real-life data
ER Boluda, SR Ferreiro, OM Moral… - Journal of Pediatric …, 2020 - journals.lww.com
Objectives: The aim of the study was to describe the experience with teduglutide of several
Spanish hospitals in pediatric patients with SBS (SBS). Methods: Seventeen pediatric …
Spanish hospitals in pediatric patients with SBS (SBS). Methods: Seventeen pediatric …
Six-month outcomes of teduglutide treatment in adult patients with short bowel syndrome with chronic intestinal failure: A real-world French observational cohort study
Background & aims Teduglutide, a GLP-2-analog, has proven effective in two placebo-
controlled studies in reducing parenteral support (PS) in patients with short bowel syndrome …
controlled studies in reducing parenteral support (PS) in patients with short bowel syndrome …
Experience with teduglutide treatment for short bowel syndrome in clinical practice
S Pevny, S Maasberg, A Rieger, M Karber, E Blüthner… - Clinical Nutrition, 2019 - Elsevier
Background & aims Teduglutide, a glucagon-like peptide 2 (GLP-2) analog, is an approved
medication specific for short bowel syndrome patients with chronic intestinal failure (SBS-IF) …
medication specific for short bowel syndrome patients with chronic intestinal failure (SBS-IF) …