It is a tough challenge for many decades to decipher the complex relationships between cell
behaviors and cellular physical properties. Single particle tracking (SPT) with high spatial …

Probe choice in single-molecule microscopy requires deeper evaluations than those
adopted for less sensitive fluorescence microscopy studies. Indeed, fluorophore …

When B cells encounter antigens on the surface of an antigen-presenting cell (APC), B cell
receptors (BCRs) are gathered into microclusters that recruit signaling enzymes. These …

Antibodies and their conjugates of fluorescent labels are widely applied in life sciences
research and clinical pathology. Among diverse label types, compact quantum dots (QDs) …

The gastrointestinal (GI) tract is lined with a layer of viscoelastic mucus gel, characterized by
a dense network of entangled and cross-linked mucins together with an abundance of …

The gastrointestinal (GI) mucosa is coated with a continuously secreted mucus layer that
serves as the first line of defense against invading enteric bacteria. We have previously …

The use of nanometer-sized semiconductor crystals, known as quantum dots, allows us to
directly observe individual biomolecular transactions through a fluorescence microscope …

The dynamic modulation of receptor diffusion-trap** at inhibitory synapses is crucial to
synaptic transmission, stability, and plasticity. In this review article, we will outline the …

Single particle tracking (SPT) combined with total internal reflection fluorescence
microscopy (TIRFm) is an outstanding approach to decipher mechanisms on the cell …

Single particle tracking (SPT), where individual molecules are fluorescently labelled and
followed over time, is an important tool that allows the spatiotemporal dynamics of …