The four-dimensional nucleome (4DN) consortium studies the architecture of the genome
and the nucleus in space and time. We summarize progress by the consortium and highlight …

Life exists in three dimensions, but until the turn of the century most electron microscopy
methods provided only 2D image data. Recently, electron microscopy techniques capable of …

Although fluorescence microscopy is ubiquitous in biomedical research, microscopy
methods reporting is inconsistent and perhaps undervalued. We emphasize the importance …

A growing community is constructing a next-generation file format (NGFF) for bioimaging to
overcome problems of scalability and heterogeneity. Organized by the Open Microscopy …

The imminent release of tissue atlases combining multichannel microscopy with single-cell
sequencing and other omics data from normal and diseased specimens creates an urgent …

The community-driven initiative Quality Assessment and Reproducibility for Instruments &
Images in Light Microscopy (QUAREP-LiMi) wants to improve reproducibility for light …

Although there is a need to demonstrate reproducibility in light microscopy acquisitions, the
lack of standardized guidelines monitoring microscope health status over time has so far …

Technological advancements in biology and microscopy have empowered a transition from
bioimaging as an observational method to a quantitative one. However, as biologists are …

Light microscopy enables researchers to observe cellular mechanisms with high spatial and
temporal resolution. However, the increasing complexity of current imaging technologies …

Imaging technologies are used throughout the life and biomedical sciences to understand
mechanisms in biology and diagnosis and therapy in animal and human medicine. We …