Artificial cells: past, present and future

W Jiang, Z Wu, Z Gao, M Wan, M Zhou, C Mao… - ACS nano, 2022 - ACS Publications
Artificial cells are constructed to imitate natural cells and allow researchers to explore
biological process and the origin of life. The construction methods for artificial cells, through …

[HTML][HTML] Recent advances in using liposomes for delivery of nucleic acid-based therapeutics

H Nsairat, W Alshaer, F Odeh, E Esawi, D Khater… - OpenNano, 2023 - Elsevier
Nucleic acid therapeutics are rapidly expanding because of recent advancements in
production and purification. This class of therapeutics may change the field of disease …

Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape

JH Lorent, KR Levental, L Ganesan… - Nature chemical …, 2020 - nature.com
A fundamental feature of cellular plasma membranes (PMs) is an asymmetric lipid
distribution between the bilayer leaflets. However, neither the detailed, comprehensive …

Versatile phospholipid assemblies for functional synthetic cells and artificial tissues

X Wang, H Du, Z Wang, W Mu, X Han - Advanced Materials, 2021 - Wiley Online Library
The bottom‐up construction of a synthetic cell from nonliving building blocks capable of
mimicking cellular properties and behaviors helps to understand the particular biophysical …

Vesicle-based artificial cells: materials, construction methods and applications

Y Lu, G Allegri, J Huskens - Materials horizons, 2022 - pubs.rsc.org
The construction of artificial cells with specific cell-mimicking functions helps to explore
complex biological processes and cell functions in natural cell systems and provides an …

Exploring giant unilamellar vesicle production for artificial cells—current challenges and future directions

L Van de Cauter, L van Buren, GH Koenderink… - Small …, 2023 - Wiley Online Library
Creating an artificial cell from the bottom up is a long‐standing challenge and, while
significant progress has been made, the full realization of this goal remains elusive …

Bending rigidity, capacitance, and shear viscosity of giant vesicle membranes prepared by spontaneous swelling, electroformation, gel-assisted, and phase transfer …

HA Faizi, A Tsui, R Dimova, PM Vlahovska - Langmuir, 2022 - ACS Publications
Closed lipid bilayers in the form of giant unilamellar vesicles (GUVs) are commonly used
membrane models. Various methods have been developed to prepare GUVs, however it is …

Programmed magnetic manipulation of vesicles into spatially coded prototissue architectures arrays

Q Li, S Li, X Zhang, W Xu, X Han - Nature communications, 2020 - nature.com
In nature, cells self-assemble into spatially coded tissular configurations to execute higher-
order biological functions as a collective. This mechanism has stimulated the recent trend in …

Advances in giant unilamellar vesicle preparation techniques and applications

KS Nair, H Bajaj - Advances in Colloid and Interface Science, 2023 - Elsevier
Giant unilamellar vesicles (GUVs) are versatile and promising cell-sized bio-membrane
mimetic platforms. Their applications range from understanding and quantifying membrane …

Giant liposome formation toward the synthesis of well-defined artificial cells

K Kamiya, S Takeuchi - Journal of Materials Chemistry B, 2017 - pubs.rsc.org
Giant liposomes or giant vesicles, with a diameter ranging from 1 to 100 μm, have been
used to examine simple biophysical and biochemical processes in isolation from living cells …